Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
37906
CAS Number:
122111-03-9
Gemcitabine hydrochloride
Purity:
≥ 98% (HPLC)
Synonym(s):
2'-Deoxy-2',2'-difluorocytidine, dFdC
Documents
$124.99 /100MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Gemcitabine hydrochloride is a potent nucleoside analog widely utilized in the treatment of various cancers, including pancreatic, lung, and bladder cancers. This compound works by inhibiting DNA synthesis, effectively slowing down the growth of cancer cells. Its unique structure, featuring difluorinated and hydroxymethyl groups, enhances its efficacy and selectivity, making it a preferred choice in chemotherapy regimens. Researchers and healthcare professionals appreciate its ability to improve patient outcomes when combined with other therapeutic agents, thereby expanding treatment options in oncology.

In addition to its primary use in cancer therapy, gemcitabine hydrochloride is also being explored for its potential in combination therapies and personalized medicine approaches. Its favorable pharmacokinetic profile allows for flexible dosing schedules, which can be tailored to individual patient needs. This adaptability, along with its established safety and efficacy, positions gemcitabine hydrochloride as a critical component in the ongoing fight against cancer, making it an essential compound for both clinical and research applications.

Synonyms
2'-Deoxy-2',2'-difluorocytidine, dFdC
CAS Number
122111-03-9
Purity
≥ 98% (HPLC)
Molecular Formula
C9H11F2N3O4·HCl
Molecular Weight
299.66
MDL Number
MFCD01735988
PubChem ID
356653
Melting Point
292 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 46 - 49 ° (C=1 in H2O)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
2'-Deoxy-2',2'-difluorocytidine, dFdC
CAS Number
122111-03-9
Purity
≥ 98% (HPLC)
Molecular Formula
C9H11F2N3O4·HCl
Molecular Weight
299.66
MDL Number
MFCD01735988
PubChem ID
356653
Melting Point
292 °C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 46 - 49 ° (C=1 in H2O)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Gemcitabine hydrochloride is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily used as a chemotherapy agent for treating various cancers, including pancreatic, lung, and breast cancer. Its effectiveness in inhibiting tumor growth makes it a critical component in oncology.
  • Combination Therapies: Researchers often explore its use in combination with other drugs to enhance therapeutic efficacy. For example, pairing it with cisplatin can improve outcomes in certain cancer types.
  • Clinical Trials: Gemcitabine hydrochloride is frequently involved in clinical trials aimed at discovering new treatment regimens, providing valuable data on its effectiveness and safety in diverse patient populations.
  • Pharmaceutical Development: The compound serves as a model in pharmaceutical research for developing new nucleoside analogs, which can lead to innovative treatments for viral infections and other diseases.
  • Personalized Medicine: Its application in pharmacogenomics allows researchers to study how genetic variations affect individual responses to gemcitabine, paving the way for tailored cancer therapies that optimize patient outcomes.

Citations