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Catalog Number:
37898
CAS Number:
162359-56-0
Fingolimod hydrochloride
Purity:
≥ 98% (Assay by titration , HPLC)
Synonym(s):
2-Amino-2-[2-(4-n-octylphenyl)ethyl]propane-1,3-diol hydrochloride, FTY 720
Documents
$145.52 /200MG
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Product Information

Fingolimod hydrochloride is a potent immunomodulatory agent primarily used in the treatment of multiple sclerosis (MS). This compound functions by modulating sphingosine-1-phosphate (S1P) receptors, effectively sequestering lymphocytes in lymph nodes and preventing their migration to the central nervous system. This mechanism not only reduces the frequency of MS flare-ups but also helps in managing the progression of the disease. Fingolimod hydrochloride has gained recognition for its oral bioavailability, offering a convenient alternative to traditional injectable therapies, thus enhancing patient compliance and quality of life.

In addition to its primary application in MS, Fingolimod hydrochloride is being explored for potential uses in other autoimmune diseases and transplant rejection scenarios due to its immunosuppressive properties. Researchers are investigating its role in conditions such as psoriasis and Crohn's disease, highlighting its versatility in therapeutic applications. The compound's unique ability to cross the blood-brain barrier further underscores its significance in neurological research, making it a valuable asset for professionals in the pharmaceutical and biomedical fields.

Synonyms
2-Amino-2-[2-(4-n-octylphenyl)ethyl]propane-1,3-diol hydrochloride, FTY 720
CAS Number
162359-56-0
Purity
≥ 98% (Assay by titration , HPLC)
Molecular Formula
C19H33NO2·HCl
Molecular Weight
343.94
MDL Number
MFCD00939512
PubChem ID
107969
Melting Point
110 °C
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
General Information
Synonyms
2-Amino-2-[2-(4-n-octylphenyl)ethyl]propane-1,3-diol hydrochloride, FTY 720
CAS Number
162359-56-0
Purity
≥ 98% (Assay by titration , HPLC)
Molecular Formula
C19H33NO2·HCl
Molecular Weight
343.94
MDL Number
MFCD00939512
PubChem ID
107969
Melting Point
110 °C
Appearance
White to almost white powder to crystal
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fingolimod hydrochloride is widely utilized in research focused on

  • Treatment of Multiple Sclerosis: This compound is primarily used as a medication for relapsing forms of multiple sclerosis (MS), helping to reduce the frequency of flare-ups and slow disease progression.
  • Immunomodulation: Fingolimod acts as an immunomodulator, effectively altering immune responses, which can be beneficial in various autoimmune diseases beyond MS.
  • Cardiovascular Research: Researchers are exploring its effects on cardiovascular health, as it may influence heart rate and vascular function, providing insights for heart disease treatments.
  • Drug Development: Its unique mechanism of action makes it a valuable model in drug development studies, particularly for understanding lymphocyte trafficking and immune system modulation.
  • Combination Therapies: Fingolimod is being investigated in combination with other therapies to enhance treatment efficacy in MS and other conditions, potentially leading to more effective treatment regimens.

Citations