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Catalog Number:
35195
CAS Number:
324017-21-2
Fmoc-4-amino-D-phenylalanine
Purity:
≥ 99.5% (Chiral HPLC)
Synonym(s):
Fmoc-D-Phe(4-NH2)-OH, (R)-Fmoc-2-amino-3-(4-aminophenyl)propionic acid
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Product Information

Fmoc-4-amino-D-phenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protective group, which provides stability during the synthesis process while allowing for easy deprotection when needed. Its unique structure enhances solubility and reactivity, making it an ideal choice for researchers focused on developing complex peptides and proteins. Fmoc-4-amino-D-phenylalanine is particularly valuable in the pharmaceutical industry for the design of peptide-based therapeutics, where precise amino acid sequences are critical for biological activity.

In addition to its applications in drug discovery, this compound is also employed in academic research for studying protein interactions and functions. Its ability to facilitate the incorporation of D-amino acids into peptides allows for the exploration of novel biochemical pathways and therapeutic targets. Researchers appreciate the compound's reliability and efficiency, which can lead to faster development times and improved outcomes in peptide synthesis. With its robust profile, Fmoc-4-amino-D-phenylalanine stands out as a key reagent for advancing both scientific research and pharmaceutical innovation.

Synonyms
Fmoc-D-Phe(4-NH2)-OH, (R)-Fmoc-2-amino-3-(4-aminophenyl)propionic acid
CAS Number
324017-21-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H22N2O4
Molecular Weight
402.5
MDL Number
MFCD02682658
PubChem ID
22660102
Melting Point
189 - 192 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 10 ± 2 ° (C=1 in DMF)
Conditions
Store at RT
General Information
Synonyms
Fmoc-D-Phe(4-NH2)-OH, (R)-Fmoc-2-amino-3-(4-aminophenyl)propionic acid
CAS Number
324017-21-2
Purity
≥ 99.5% (Chiral HPLC)
Molecular Formula
C24H22N2O4
Molecular Weight
402.5
MDL Number
MFCD02682658
PubChem ID
22660102
Melting Point
189 - 192 ?C
Appearance
White to off-white powder
Optical Rotation
[a]20D = 10 ± 2 ° (C=1 in DMF)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-amino-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides efficiently.
  • Drug Development: It plays a significant role in the development of peptide-based therapeutics, particularly in targeting specific diseases, enhancing drug efficacy.
  • Bioconjugation: The chemical is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving the delivery of drugs or imaging agents.
  • Research in Neuroscience: Its unique properties make it valuable in studying neuropeptides, contributing to advancements in understanding neurological disorders.
  • Protein Engineering: This compound aids in the design of modified proteins with enhanced stability and activity, which is crucial for various biotechnological applications.

Citations