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Catalog Number:
33610
CAS Number:
1217744-26-7
Fmoc-4-fluoro-2-methyl-D-phenylalanine
Synonym(s):
Fmoc-D-Phe(4-F,2-CH3)-OH, (R-Fmoc-2-amino-4-fluoro-2-methylphenylpropionic acid
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$79.22 /100MG
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Product Information

Fmoc-4-fluoro-2-methyl-D-phenylalanine is a valuable amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorinated aromatic side chain, enhancing its stability and bioactivity, making it an excellent choice for researchers focusing on the design of novel peptides with improved pharmacological properties. Its unique Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection during synthesis, facilitating the construction of complex peptide sequences with precision.

In the pharmaceutical industry, Fmoc-4-fluoro-2-methyl-D-phenylalanine is particularly relevant for the development of peptide-based therapeutics, where its structural characteristics can lead to enhanced binding affinity and specificity. Researchers have successfully employed this compound in the synthesis of bioactive peptides, which can be used in various applications, including targeted drug delivery and the development of new treatments for diseases. Its ability to improve the pharmacokinetic profiles of peptides makes it a preferred choice for professionals in medicinal chemistry and biochemistry.

Synonyms
Fmoc-D-Phe(4-F,2-CH3)-OH, (R-Fmoc-2-amino-4-fluoro-2-methylphenylpropionic acid
CAS Number
1217744-26-7
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD12198177
PubChem ID
53398090
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-D-Phe(4-F,2-CH3)-OH, (R-Fmoc-2-amino-4-fluoro-2-methylphenylpropionic acid
CAS Number
1217744-26-7
Molecular Formula
C25H22FNO4
Molecular Weight
419.45
MDL Number
MFCD12198177
PubChem ID
53398090
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-fluoro-2-methyl-D-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the incorporation of unique amino acid residues that enhance the properties of the resulting peptides.
  • Drug Development: Its structural properties make it valuable in the design of novel pharmaceuticals, especially in targeting specific biological pathways, which can lead to more effective treatments with fewer side effects.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, improving the efficacy of drug delivery systems and diagnostic tools.
  • Research in Neuroscience: It is utilized in studies related to neurotransmitter systems, helping researchers understand the role of specific amino acids in neurological functions and disorders.
  • Protein Engineering: The unique properties of this compound facilitate the engineering of proteins with enhanced stability and activity, which is crucial for biotechnological applications and therapeutic development.

Citations