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Catalog Number:
33601
CAS Number:
1213690-82-4
Boc-4-chloro-2-fluoro-L-phenylalanine
Synonym(s):
Boc-L-Phe(4-Cl,2-F)-OH, (S-Boc-2-amino-4-chloro-2-fluorophenylpropionic acid, Boc-Phe(4-Cl,2-F)-OH
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$58.39 /100MG
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Product Information

Boc-4-chloro-2-fluoro-L-phenylalanine is a valuable amino acid derivative widely utilized in pharmaceutical research and peptide synthesis. This compound features a unique combination of a Boc (tert-butyloxycarbonyl) protecting group and halogen substitutions, making it an essential building block for the development of biologically active peptides and drug candidates. Its distinctive structure enhances the stability and solubility of peptides, facilitating their incorporation into various therapeutic applications, particularly in the fields of oncology and neurology.

Researchers appreciate Boc-4-chloro-2-fluoro-L-phenylalanine for its ability to introduce specific functional groups into peptide sequences, allowing for the exploration of structure-activity relationships. This compound has been effectively employed in the synthesis of peptide analogs that exhibit improved potency and selectivity for target receptors. Its versatility and effectiveness in modifying peptide properties make it a preferred choice for chemists and biochemists aiming to innovate in drug design and development.

Synonyms
Boc-L-Phe(4-Cl,2-F)-OH, (S-Boc-2-amino-4-chloro-2-fluorophenylpropionic acid, Boc-Phe(4-Cl,2-F)-OH
CAS Number
1213690-82-4
Molecular Formula
C14H17ClFNO4
Molecular Weight
317.74
MDL Number
MFCD12198168
PubChem ID
53398087
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Boc-L-Phe(4-Cl,2-F)-OH, (S-Boc-2-amino-4-chloro-2-fluorophenylpropionic acid, Boc-Phe(4-Cl,2-F)-OH
CAS Number
1213690-82-4
Molecular Formula
C14H17ClFNO4
Molecular Weight
317.74
MDL Number
MFCD12198168
PubChem ID
53398087
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-4-chloro-2-fluoro-L-phenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in the development of peptide-based drugs, enhancing the efficacy of therapeutic agents.
  • Drug Development: Its unique structure allows researchers to modify existing pharmaceutical compounds, potentially leading to new treatments for various diseases, including cancer and neurodegenerative disorders.
  • Bioconjugation: The compound can be used in bioconjugation processes, where it helps to attach drugs or imaging agents to biomolecules, improving the targeting and effectiveness of therapies.
  • Research in Neuroscience: It is instrumental in studying neurotransmitter systems due to its structural similarity to certain amino acids, aiding in the understanding of neurological functions and disorders.
  • Custom Synthesis: Laboratories often employ this compound for custom synthesis projects, allowing for tailored solutions in research and development, particularly in medicinal chemistry.

Citations