Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
33571
CAS Number:
186046-82-2
Fmoc-PNA-A(Bhoc)-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-A(Bhoc)-Aeg-OH, PNA A Monomer
Documents
$113.87 /25MG
Pack Size Availability Price
Request Bulk Quote
Product Information

Fmoc-PNA-A(Bhoc)-OH is a versatile compound widely utilized in the field of nucleic acid chemistry and peptide synthesis. This compound, known for its unique structure, features a fluorenylmethoxycarbonyl (Fmoc) protecting group that enhances its stability and solubility, making it an ideal choice for researchers engaged in the synthesis of peptide nucleic acids (PNAs). Its application extends to the development of novel therapeutic agents, where it plays a crucial role in gene regulation and antisense technology. The incorporation of the benzhydryloxycarbonyl (Bhoc) group further enhances its utility in solid-phase synthesis, allowing for efficient coupling reactions and improved yields.

Researchers and industry professionals benefit from using Fmoc-PNA-A(Bhoc)-OH due to its ability to facilitate the design of PNA oligomers with high specificity and affinity for complementary DNA and RNA sequences. This characteristic is particularly advantageous in applications such as molecular diagnostics, drug development, and gene therapy. The compound's robust performance in various synthesis protocols positions it as a valuable tool for advancing research in genetic engineering and molecular biology.

Synonyms
Fmoc-A(Bhoc)-Aeg-OH, PNA A Monomer
CAS Number
186046-82-2
Purity
≥ 98% (HPLC)
Molecular Formula
C40H35N7O7
Molecular Weight
725.75
MDL Number
MFCD01940757
PubChem ID
11479638
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-A(Bhoc)-Aeg-OH, PNA A Monomer
CAS Number
186046-82-2
Purity
≥ 98% (HPLC)
Molecular Formula
C40H35N7O7
Molecular Weight
725.75
MDL Number
MFCD01940757
PubChem ID
11479638
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-PNA-A(Bhoc)-OH is widely utilized in research focused on:

  • Peptide Nucleic Acid (PNA) Synthesis: This compound serves as a key building block in the synthesis of PNAs, which are important for gene targeting and antisense applications. Researchers benefit from its stability and specificity in binding to DNA and RNA.
  • Drug Development: In pharmaceutical research, it is used to create novel therapeutic agents that can effectively target specific genetic sequences, offering potential treatments for genetic disorders and cancers.
  • Biotechnology: The compound is applied in the development of biosensors, enhancing the detection of specific nucleic acid sequences. This is crucial for diagnostics in clinical settings, providing rapid and accurate results.
  • Gene Therapy: Its role in gene therapy research is significant, as it aids in the design of oligonucleotides that can modify gene expression, offering promising avenues for treating various diseases.
  • Research in Molecular Biology: Fmoc-PNA-A(Bhoc)-OH is utilized in studies exploring the interactions between nucleic acids and proteins, helping scientists understand fundamental biological processes and develop new molecular tools.

Citations