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Catalog Number:
33569
CAS Number:
169396-92-3
Fmoc-PNA-T-OH
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-T-Aeg-OH, PNA T Monomer
Documents
$105.70 /25MG
Pack Size Availability Price
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Product Information

Fmoc-PNA-T-OH is a versatile compound widely utilized in the field of nucleic acid chemistry, particularly in the synthesis of peptide nucleic acids (PNAs). This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective deprotection of amino acids during solid-phase synthesis. Its unique structure allows for the incorporation of modified nucleobases, making it an invaluable tool for researchers focused on developing novel antisense oligonucleotides and gene therapy applications.

The compound's stability and compatibility with various coupling reagents enhance its utility in the synthesis of PNA oligomers, which are known for their high binding affinity and specificity to complementary DNA and RNA sequences. This property makes Fmoc-PNA-T-OH particularly advantageous in applications such as molecular diagnostics, targeted gene regulation, and the development of innovative therapeutic strategies. Researchers will appreciate its ability to facilitate the creation of complex nucleic acid structures with improved efficacy compared to traditional nucleic acid chemistries.

Synonyms
Fmoc-T-Aeg-OH, PNA T Monomer
CAS Number
169396-92-3
Purity
≥ 98% (HPLC)
Molecular Formula
C26H26N4O7
Molecular Weight
506.51
MDL Number
MFCD01940758
PubChem ID
13009309
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
Fmoc-T-Aeg-OH, PNA T Monomer
CAS Number
169396-92-3
Purity
≥ 98% (HPLC)
Molecular Formula
C26H26N4O7
Molecular Weight
506.51
MDL Number
MFCD01940758
PubChem ID
13009309
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-PNA-T-OH is widely utilized in research focused on:

  • Peptide Nucleic Acid (PNA) Synthesis: This compound serves as a key building block in the synthesis of PNAs, which are important for gene targeting and antisense applications. Researchers can create more stable and specific nucleic acid analogs for therapeutic purposes.
  • Drug Development: In pharmaceutical research, Fmoc-PNA-T-OH is used to develop novel drugs that can effectively target specific RNA sequences. This can lead to advancements in treatments for genetic disorders and cancers.
  • Diagnostics: The compound plays a role in the creation of diagnostic tools that utilize PNA probes for detecting specific DNA or RNA sequences in clinical samples, enhancing the accuracy of genetic testing.
  • Biotechnology: In the biotechnology sector, it is employed in the design of biosensors that can detect biomolecules, offering a reliable method for monitoring biological processes in real-time.
  • Research in Molecular Biology: Fmoc-PNA-T-OH is instrumental in molecular biology studies, allowing researchers to explore gene function and regulation through the use of PNA-based techniques, which can provide insights into cellular mechanisms.

Citations