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Catalog Number:
33070
CAS Number:
865-47-4
Potassium tert-butoxide solution, 2.0 M in THF
Purity:
≥ 99% (Assay by titration)
Synonym(s):
Potassium tert-butylate solution
Hazmat
Documents
$25.00 /100ML
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Product Information

Potassium tert-butoxide solution, 2.0 M in THF, is a highly effective and versatile reagent widely utilized in organic synthesis and chemical research. This strong base is particularly valued for its ability to deprotonate a variety of substrates, making it an essential tool in the formation of carbon-carbon bonds and the synthesis of complex organic molecules. Its solubility in tetrahydrofuran (THF) enhances its reactivity and compatibility with numerous organic reactions, including elimination reactions and nucleophilic substitutions. Researchers and industry professionals appreciate its efficiency in facilitating reactions that require a strong base, such as the generation of enolates and the synthesis of alkynes.

This potassium tert-butoxide solution is particularly advantageous due to its high concentration, allowing for more efficient reactions and reduced solvent use. Its application extends to the pharmaceutical and agrochemical industries, where it plays a crucial role in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals. With its reliable performance and broad applicability, potassium tert-butoxide solution is an indispensable reagent for chemists seeking to optimize their synthetic pathways and enhance reaction yields.

Synonyms
Potassium tert-butylate solution
CAS Number
865-47-4
Purity
≥ 99% (Assay by titration)
Molecular Formula
C4H9OK
Molecular Weight
112.21
MDL Number
MFCD00012162
PubChem ID
23665647
Density
0.929 g/cm3
Appearance
Colorless to yellowish brown liquid
Conditions
Store at RT
General Information
Synonyms
Potassium tert-butylate solution
CAS Number
865-47-4
Purity
≥ 99% (Assay by titration)
Molecular Formula
C4H9OK
Molecular Weight
112.21
MDL Number
MFCD00012162
PubChem ID
23665647
Density
0.929 g/cm3
Appearance
Colorless to yellowish brown liquid
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Potassium tert-butoxide solution, 2.0 M in THF is widely utilized in research focused on:

  • Organic Synthesis: This solution serves as a strong base in various organic reactions, facilitating the deprotonation of weak acids and enabling the formation of carbon-carbon bonds.
  • Pharmaceutical Development: In the pharmaceutical industry, it is used to synthesize complex molecules, aiding in the development of new drugs and therapeutic agents.
  • Polymer Chemistry: Researchers utilize this chemical in the production of polymers, where it acts as a catalyst in polymerization reactions, enhancing material properties.
  • Grignard Reactions: It plays a crucial role in Grignard reactions, allowing for the formation of organometallic compounds that are essential in various chemical syntheses.
  • Laboratory Research: Its use in laboratories for various experimental setups helps in understanding reaction mechanisms and developing new synthetic methodologies.

Citations