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Catalog Number:
33033
CAS Number:
201608-12-0
Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt
Synonym(s):
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) trifluoroacetate salt, Caspase-1 Inhibitor I, Cell-Permeable
Documents
$144.12 /1MG
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Product Information

The Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt is a potent compound designed for research applications focused on inflammation and cell death pathways. This inhibitor specifically targets caspase-1, an essential enzyme involved in the activation of inflammatory cytokines, making it a valuable tool for studying various inflammatory diseases and conditions. Its cell-permeable nature allows for effective intracellular delivery, facilitating in vivo studies and enhancing the accuracy of experimental results. Researchers can utilize this compound to explore therapeutic strategies for conditions such as autoimmune diseases, neurodegenerative disorders, and other inflammation-related pathologies.

In addition to its primary function as a caspase-1 inhibitor, this compound offers unique advantages over similar inhibitors, including improved solubility and bioavailability, which are crucial for achieving effective concentrations in biological systems. Its versatility makes it suitable for various applications, from basic research to drug development, providing insights into the mechanisms of inflammation and cell death. By incorporating this inhibitor into their studies, researchers can gain a deeper understanding of disease mechanisms and potentially identify novel therapeutic targets.

Synonyms
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) trifluoroacetate salt, Caspase-1 Inhibitor I, Cell-Permeable
CAS Number
201608-12-0
Molecular Formula
C97H160N20O24·C2HF3O2
Molecular Weight
2104.44
MDL Number
MFCD31692292
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) trifluoroacetate salt, Caspase-1 Inhibitor I, Cell-Permeable
CAS Number
201608-12-0
Molecular Formula
C97H160N20O24·C2HF3O2
Molecular Weight
2104.44
MDL Number
MFCD31692292
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Cell-permeable Caspase-1 Inhibitor I trifluoroacetate salt is widely utilized in research focused on:

  • Inflammation Research: This compound helps scientists study the role of caspase-1 in inflammatory processes, allowing for a deeper understanding of diseases like rheumatoid arthritis and inflammatory bowel disease.
  • Drug Development: It serves as a valuable tool in the development of new anti-inflammatory drugs, providing insights into how inhibiting caspase-1 can lead to therapeutic benefits.
  • Cell Signaling Studies: Researchers use this inhibitor to explore cell signaling pathways, particularly those involved in apoptosis and necrosis, enhancing knowledge in cancer research.
  • Neurodegenerative Disease Research: The compound is applied in studies related to neurodegenerative diseases, helping to elucidate the mechanisms of cell death and potential protective strategies.
  • Biomarker Discovery: It aids in the identification of biomarkers for various diseases, facilitating early diagnosis and treatment strategies by understanding how caspase-1 activity correlates with disease states.

Citations