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Catalog Number:
33008
CAS Number:
350228-37-4
(Asn670,Sta671,Va672-Amyloid β/A4 Protein Precursor770 (662-675) ammonium salt
Synonym(s):
H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe-OH ammonium salt, (Asn670,Sta671,Val672)-APP770 (662-675)
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Product Information

The (Asn670,Sta671,Va672)-Amyloid β/A4 Protein Precursor770 (662-675) ammonium salt is a significant compound in the field of biomedical research, particularly in studies related to neurodegenerative diseases such as Alzheimer's. This protein precursor plays a crucial role in the formation of amyloid plaques, which are characteristic of Alzheimer's pathology. Researchers utilize this compound to investigate the mechanisms of amyloid aggregation and its implications in neurodegeneration, making it invaluable for drug discovery and therapeutic development.

With its complex structure, this ammonium salt variant offers unique properties that enhance solubility and stability, facilitating its use in various experimental settings. It is particularly beneficial for in vitro studies, allowing scientists to explore the interactions between amyloid proteins and potential inhibitors. The compound's ability to mimic physiological conditions makes it an essential tool for researchers aiming to develop effective treatments for Alzheimer's disease and related disorders. Its relevance in advancing our understanding of protein misfolding and aggregation processes underscores its importance in the pharmaceutical and biotechnology industries.

Synonyms
H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe-OH ammonium salt, (Asn670,Sta671,Val672)-APP770 (662-675)
CAS Number
350228-37-4
Molecular Formula
C73H118N16O27·NH3
Molecular Weight
1668.83
MDL Number
MFCD18633341
PubChem ID
44135344
Conditions
Store at ≤ -10 °C
General Information
Synonyms
H-Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe-OH ammonium salt, (Asn670,Sta671,Val672)-APP770 (662-675)
CAS Number
350228-37-4
Molecular Formula
C73H118N16O27·NH3
Molecular Weight
1668.83
MDL Number
MFCD18633341
PubChem ID
44135344
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(Asn670,Sta671,Va672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt is widely utilized in research focused on:

  • Neuroscience Research: This compound is crucial for studying Alzheimer's disease, as it plays a role in the formation of amyloid plaques. Researchers use it to understand the mechanisms behind neurodegeneration.
  • Drug Development: In pharmaceutical research, it serves as a target for developing new drugs aimed at preventing or treating Alzheimer's. Its properties help in screening potential therapeutic candidates.
  • Biomarker Studies: It is used in identifying biomarkers for early detection of neurodegenerative diseases, aiding in the development of diagnostic tools that can improve patient outcomes.
  • Protein Interaction Studies: The compound is essential for studying protein-protein interactions, which can provide insights into cellular processes and disease mechanisms, particularly in neurobiology.
  • Therapeutic Research: It is involved in the exploration of peptide-based therapies, offering potential advantages over traditional treatments by targeting specific pathways involved in amyloid formation.

Citations