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Catalog Number:
33004
CAS Number:
1802078-31-4
Mca-(Asn670,Leu671-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) ammonium acetate salt
Synonym(s):
Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH ammonium acetate salt
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Product Information

Mca-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)-Lys(Dnp) ammonium acetate salt is a specialized peptide that plays a crucial role in research related to Alzheimer's disease and neurodegenerative disorders. This compound is a modified version of the amyloid precursor protein, which is significant in the formation of amyloid plaques, a hallmark of Alzheimer's pathology. Researchers utilize this compound to study the mechanisms of amyloid plaque formation and to develop potential therapeutic strategies. Its unique structure, featuring a dinitrophenyl (Dnp) modification, enhances its stability and allows for more precise interactions in biochemical assays.

This compound is particularly valuable in the fields of biochemistry and pharmacology, where it aids in the exploration of amyloid-related pathways and the development of inhibitors that could mitigate the effects of amyloid accumulation. Its application extends to drug discovery and the testing of new therapeutic agents aimed at treating Alzheimer's disease. By providing insights into amyloid pathology, this compound supports the advancement of research that could lead to innovative treatments, making it an essential tool for researchers and industry professionals focused on neurodegenerative diseases.

Synonyms
Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH ammonium acetate salt
CAS Number
1802078-31-4
Molecular Formula
C68H88N14O27·C2H7NO2
Molecular Weight
1610.58
MDL Number
MFCD31692286
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-OH ammonium acetate salt
CAS Number
1802078-31-4
Molecular Formula
C68H88N14O27·C2H7NO2
Molecular Weight
1610.58
MDL Number
MFCD31692286
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mca-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)-Lys(Dnp) ammonium acetate salt is widely utilized in research focused on:

  • Neuroscience Research: This compound is instrumental in studying amyloid-beta peptide aggregation, which is crucial for understanding Alzheimer's disease pathology.
  • Drug Development: It serves as a valuable tool in the development of therapeutics aimed at preventing or reversing amyloid plaque formation, offering potential treatments for neurodegenerative diseases.
  • Biomarker Identification: Researchers use this compound to identify biomarkers for early detection of Alzheimer's, enhancing diagnostic capabilities in clinical settings.
  • Protein Interaction Studies: It facilitates the investigation of protein-protein interactions, helping scientists understand the molecular mechanisms behind amyloid-related disorders.
  • Therapeutic Target Validation: This compound aids in validating therapeutic targets in the amyloid cascade hypothesis, providing insights into effective treatment strategies.

Citations