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Catalog Number:
33001
CAS Number:
1802078-32-5
Mca-(Asn670,Leu671-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide ammonium salt
Synonym(s):
Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-NH2 ammonium salt, Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp) amide
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Product Information

Mca-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide ammonium salt is a specialized peptide compound that plays a crucial role in biomedical research, particularly in the study of neurodegenerative diseases such as Alzheimer's. This compound is a derivative of the amyloid precursor protein, which is significant in the formation of amyloid plaques, a hallmark of Alzheimer's disease. Researchers utilize this compound to investigate the mechanisms of amyloid plaque formation and to develop potential therapeutic strategies. Its unique structure, featuring a dinitrophenyl (Dnp) modification, enhances its stability and bioactivity, making it an invaluable tool for studying protein interactions and cellular processes.

This compound is particularly beneficial for researchers focused on peptide synthesis and modification, as well as those exploring neurobiology and pharmacology. Its application extends to drug development, where understanding the interactions of amyloid proteins can lead to innovative treatments for Alzheimer's and related disorders. The compound's specific modifications allow for targeted studies, providing insights that could pave the way for breakthroughs in neurodegenerative disease therapies.

Synonyms
Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-NH2 ammonium salt, Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp) amide
CAS Number
1802078-32-5
Molecular Formula
C68H89N15O26·NH3
Molecular Weight
1549.55
MDL Number
MFCD31692285
PubChem ID
171369912
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Mca-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Lys(Dnp)-NH2 ammonium salt, Mca-(Asn670,Leu671)-APP770 (667-675)-Lys(Dnp) amide
CAS Number
1802078-32-5
Molecular Formula
C68H89N15O26·NH3
Molecular Weight
1549.55
MDL Number
MFCD31692285
PubChem ID
171369912
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mca-(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide ammonium salt is widely utilized in research focused on:

  • Neuroscience Research: This compound plays a crucial role in studying Alzheimer's disease by mimicking amyloid beta peptides, helping researchers understand the mechanisms of amyloid plaque formation.
  • Drug Development: It serves as a valuable tool in the development of therapeutic agents targeting amyloid beta aggregation, potentially leading to new treatments for neurodegenerative disorders.
  • Biochemical Assays: The compound is used in various assays to evaluate the efficacy of drugs aimed at reducing amyloid beta levels, providing insights into their potential effectiveness.
  • Protein Interaction Studies: It aids in investigating protein-protein interactions within the amyloid pathway, which is essential for identifying new drug targets.
  • Diagnostic Applications: This chemical can be utilized in the development of diagnostic tools that detect amyloid beta levels in biological samples, assisting in early diagnosis of Alzheimer's disease.

Citations