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Catalog Number:
32802
CAS Number:
103476-89-7
Leupeptin
Purity:
≥ 97% (HPLC)
Synonym(s):
Ac-Leu-Leu-Arg-aldehyde · sulfate salt
Documents
$80.00 /5MG
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Product Information

Leupeptin is a potent protease inhibitor widely utilized in biochemical research and pharmaceutical applications. This compound is particularly effective in inhibiting serine and cysteine proteases, making it invaluable for studies involving protein degradation and cellular processes. Researchers often employ Leupeptin to preserve protein integrity during cell lysis and extraction, ensuring accurate analysis of protein function and interactions. Its ability to stabilize proteins has made it a critical component in various assays, including those focused on apoptosis and signal transduction pathways.

In addition to its research applications, Leupeptin has shown promise in therapeutic contexts, particularly in the development of treatments for diseases characterized by abnormal protease activity. Its unique properties allow for enhanced specificity and reduced side effects compared to other protease inhibitors, making it a preferred choice among professionals in biochemistry and molecular biology. With its versatile applications, Leupeptin stands out as an essential tool for researchers aiming to unlock the complexities of protein dynamics.

Synonyms
Ac-Leu-Leu-Arg-aldehyde · sulfate salt
CAS Number
103476-89-7
Purity
≥ 97% (HPLC)
Molecular Formula
2C20H38N6O4·H2SO4
Molecular Weight
951.2
MDL Number
MFCD00081028
PubChem ID
44134798
Appearance
White powder
Optical Rotation
[a]D20 = -80 to -69 ° (C=1 in water)
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Ac-Leu-Leu-Arg-aldehyde · sulfate salt
CAS Number
103476-89-7
Purity
≥ 97% (HPLC)
Molecular Formula
2C20H38N6O4·H2SO4
Molecular Weight
951.2
MDL Number
MFCD00081028
PubChem ID
44134798
Appearance
White powder
Optical Rotation
[a]D20 = -80 to -69 ° (C=1 in water)
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Leupeptin is widely utilized in research focused on:

  • Protease Inhibition: It is commonly used to inhibit serine and cysteine proteases, making it valuable in studies involving protein degradation and processing.
  • Cell Culture: Researchers use leupeptin in cell culture systems to prevent proteolytic degradation of proteins, ensuring the stability of important cellular components during experiments.
  • Drug Development: In pharmaceutical research, it aids in the identification of potential drug targets by preserving the integrity of proteins involved in disease pathways.
  • Biochemical Assays: Leupeptin is employed in various biochemical assays to study enzyme activity, particularly in the context of cancer research and other diseases where protease activity is altered.
  • Neuroscience Research: It is used to study neuropeptide processing and signaling, helping to uncover mechanisms of neurodegenerative diseases and potential therapeutic approaches.

Citations