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Catalog Number:
29711
CAS Number:
1313054-86-2
S-Fmoc-2-amino-3-(N-Pbf-guanidino)-propionic acid
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Agp(Pbf)-OH
Documents
$86.23 /25MG
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Product Information

(S)-Fmoc-2-amino-3-(N'-Pbf-guanidino)-propionic acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during solid-phase peptide synthesis. Its unique structure, incorporating a guanidino group, enhances its potential in creating bioactive peptides, particularly those with therapeutic applications in areas such as oncology and immunology.

Researchers and industry professionals appreciate the compound's stability and ease of use, which facilitate the synthesis of complex peptides with high purity and yield. Its ability to form stable interactions with biological targets makes it an attractive candidate for the development of peptide-based drugs. Furthermore, the incorporation of the Pbf (2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl) group provides additional functional versatility, allowing for the exploration of novel peptide structures and functions. This compound is an essential tool for advancing peptide chemistry and drug discovery.

Synonyms
Fmoc-L-Agp(Pbf)-OH
CAS Number
1313054-86-2
Purity
≥ 98% (HPLC)
Molecular Formula
C32H36N4O7S
Molecular Weight
620.72
MDL Number
MFCD15142008
PubChem ID
138114631
Appearance
White powder
Optical Rotation
[a]D20 = -13 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Agp(Pbf)-OH
CAS Number
1313054-86-2
Purity
≥ 98% (HPLC)
Molecular Formula
C32H36N4O7S
Molecular Weight
620.72
MDL Number
MFCD15142008
PubChem ID
138114631
Appearance
White powder
Optical Rotation
[a]D20 = -13 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-3-(N'-Pbf-guanidino)-propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in the development of therapeutic agents. Its protective groups facilitate the formation of complex peptide chains while ensuring stability during reactions.
  • Drug Development: In pharmaceutical research, it is employed to create novel drug candidates, especially in the field of oncology and immunology. The guanidino group enhances biological activity, making it a valuable component in drug formulation.
  • Bioconjugation: It is used in bioconjugation techniques to attach biomolecules to surfaces or other molecules. This application is crucial in creating targeted drug delivery systems and diagnostic tools.
  • Protein Engineering: Researchers utilize this compound to modify proteins for enhanced functionality. Its unique structure allows for the introduction of specific properties, aiding in the design of proteins with tailored characteristics for industrial applications.
  • Research in Molecular Biology: This chemical is instrumental in studies involving gene expression and regulation. Its ability to interact with various biomolecules makes it a useful tool for understanding complex biological processes.

Citations