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Catalog Number:
22106
CAS Number:
42540-40-9
Cefamandole nafate
Purity:
≥810 ॖg/mg anhydrous basis
Synonym(s):
Cefamandole formate sodium salt, (6R,7R-7-(2-Formyloxy-2-phenylacetylamino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate sodium
Antibiotic
Documents
$20.00 /1G
Pack Size Availability Price
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Product Information

Cefamandole nafate is a semisynthetic cephalosporin antibiotic, renowned for its effectiveness against a broad spectrum of bacterial infections. This compound is particularly valuable in clinical settings, as it exhibits potent activity against both Gram-positive and Gram-negative bacteria, making it a versatile choice for treating various infections, including respiratory tract infections, skin infections, and urinary tract infections. Its unique structure enhances its stability against beta-lactamases, which are enzymes produced by certain bacteria that can render other antibiotics ineffective.

In addition to its therapeutic applications, Cefamandole nafate is utilized in research settings to study antibiotic resistance and the mechanisms of bacterial infection. Its ability to penetrate bacterial cell walls effectively allows researchers to explore its interactions with different bacterial strains, providing insights that can lead to the development of new antimicrobial strategies. The compound's favorable pharmacokinetic properties, including its absorption and distribution, further support its use in both clinical and laboratory environments, making it an essential tool for healthcare professionals and researchers alike.

Synonyms
Cefamandole formate sodium salt, (6R,7R-7-(2-Formyloxy-2-phenylacetylamino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate sodium
CAS Number
42540-40-9
Purity
≥810 ॖg/mg anhydrous basis
Molecular Formula
C19H17N6O6S2Na
Molecular Weight
512.49
MDL Number
MFCD00864877
PubChem ID
23669253
Appearance
White to off-white powder
Conditions
Store at 0-8°C
General Information
Synonyms
Cefamandole formate sodium salt, (6R,7R-7-(2-Formyloxy-2-phenylacetylamino)-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate sodium
CAS Number
42540-40-9
Purity
≥810 ॖg/mg anhydrous basis
Molecular Formula
C19H17N6O6S2Na
Molecular Weight
512.49
MDL Number
MFCD00864877
PubChem ID
23669253
Appearance
White to off-white powder
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Cefamandole nafate is widely utilized in research focused on:

  • Antibiotic Therapy: This compound is primarily used as a broad-spectrum antibiotic, effective against various bacterial infections, particularly in hospital settings where resistant strains may be present.
  • Clinical Trials: It plays a significant role in clinical research for developing new antibiotic therapies, helping researchers understand its efficacy and safety in treating infections.
  • Pharmaceutical Formulations: Cefamandole nafate is incorporated into formulations for injectable antibiotics, providing healthcare professionals with effective treatment options for serious infections.
  • Microbiology Studies: Researchers utilize this compound in microbiology to study bacterial resistance patterns, contributing to the development of new strategies to combat antibiotic resistance.
  • Veterinary Medicine: It is also applied in veterinary practices to treat infections in animals, ensuring their health and well-being while minimizing the risk of antibiotic resistance.

Citations