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Catalog Number:
22058
CAS Number:
294-93-9
12-Crown-4
Purity:
98 - 100% (GC)
Synonym(s):
1,4,7,10-Tetraoxacyclododecane, 12-Crown 4-ether
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Product Information

12-Crown-4 is a versatile crown ether known for its ability to selectively complex with alkali metal cations, particularly potassium ions. This unique property makes it invaluable in various applications, including ion-selective electrodes, extraction processes, and as a phase transfer catalyst in organic synthesis. Researchers and industry professionals utilize 12-Crown-4 for its efficiency in enhancing reaction rates and improving product yields, particularly in the synthesis of pharmaceuticals and fine chemicals. Its ability to solubilize ionic compounds in nonpolar solvents opens up new pathways for chemical reactions that would otherwise be challenging.

In analytical chemistry, 12-Crown-4 is frequently employed in the development of sensors and separation techniques, allowing for precise measurements and extractions. Its compatibility with a wide range of solvents and its stability under various conditions further enhance its appeal in both laboratory and industrial settings. With its proven track record and broad applicability, 12-Crown-4 remains a crucial compound for those seeking to optimize their chemical processes and achieve superior results.

Synonyms
1,4,7,10-Tetraoxacyclododecane, 12-Crown 4-ether
CAS Number
294-93-9
Purity
98 - 100% (GC)
Molecular Formula
C8H16O4
Molecular Weight
176.21
MDL Number
MFCD00005103
PubChem ID
9269
Melting Point
16 °C (Lit.)
Density
1.089 g/mL at 25 °C
Appearance
Colorless liquid
Boiling Point
61 - 70 °C / 0.5 mmHg
Refractive Index
n20/D 1.463
Conditions
Store at 0 - 8 °C
General Information
Synonyms
1,4,7,10-Tetraoxacyclododecane, 12-Crown 4-ether
CAS Number
294-93-9
Purity
98 - 100% (GC)
Molecular Formula
C8H16O4
Molecular Weight
176.21
MDL Number
MFCD00005103
PubChem ID
9269
Melting Point
16 °C (Lit.)
Density
1.089 g/mL at 25 °C
Appearance
Colorless liquid
Boiling Point
61 - 70 °C / 0.5 mmHg
Refractive Index
n20/D 1.463
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

12-Crown-4 is widely utilized in research focused on:

  • Ion Selectivity: This compound is excellent for selectively binding cations, particularly potassium ions, making it valuable in electrochemical sensors and analytical chemistry.
  • Extraction Processes: It is frequently used in solvent extraction methods to separate and purify metal ions from solutions, benefiting industries like mining and recycling.
  • Polymer Chemistry: 12-Crown-4 serves as a building block in the synthesis of polymeric materials, enhancing properties such as ion conductivity in applications like batteries and fuel cells.
  • Drug Delivery Systems: Its ability to form complexes with various drugs allows for improved solubility and bioavailability, making it useful in pharmaceutical formulations.
  • Research in Supramolecular Chemistry: This compound plays a significant role in the study of molecular recognition and self-assembly, aiding in the development of new materials and nanotechnology.

Citations