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Catalog Number:
15504
CAS Number:
331763-60-1
Fmoc-4-chloro-D-ॆ-homophenylalanine
Purity:
≥ 98% (Assay)
Synonym(s):
Fmoc-D-β-HomoPhe(4-Cl)-OH, Fmoc-(R)-3-amino-4-(4-chlorophenyl)butyric acid
Documents
$79.22 /100MG
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Product Information

Fmoc-4-chloro-D-b-homophenylalanine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group, which facilitates the selective protection of amino groups during the synthesis of peptides. Its chlorinated phenyl group enhances the compound's reactivity, making it an excellent choice for researchers aiming to create complex peptide structures with specific biological activities.

In the pharmaceutical industry, Fmoc-4-chloro-D-b-homophenylalanine is particularly valuable for developing peptide-based therapeutics, including those targeting cancer and metabolic disorders. Its ability to incorporate into various peptide sequences allows for the exploration of structure-activity relationships, enabling researchers to optimize drug candidates effectively. Additionally, its stability under various reaction conditions ensures reliable performance in laboratory settings, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-D-β-HomoPhe(4-Cl)-OH, Fmoc-(R)-3-amino-4-(4-chlorophenyl)butyric acid
CAS Number
331763-60-1
Purity
≥ 98% (Assay)
Molecular Formula
C25H22ClNO4
Molecular Weight
435.91
MDL Number
MFCD01860904
PubChem ID
44181917
Appearance
White powder
Optical Rotation
[á]D20 = 20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-D-β-HomoPhe(4-Cl)-OH, Fmoc-(R)-3-amino-4-(4-chlorophenyl)butyric acid
CAS Number
331763-60-1
Purity
≥ 98% (Assay)
Molecular Formula
C25H22ClNO4
Molecular Weight
435.91
MDL Number
MFCD01860904
PubChem ID
44181917
Appearance
White powder
Optical Rotation
[á]D20 = 20 ± 2 º (C=1 in DMF)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4-chloro-D-b-homophenylalanine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as an important building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing for the creation of complex peptide structures.
  • Drug Development: Its unique properties make it valuable in the pharmaceutical industry for developing novel therapeutics, especially in targeting specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation processes, enabling the attachment of peptides to various biomolecules, which is crucial for creating targeted drug delivery systems.
  • Research in Neuroscience: It is applied in studies related to neuropeptides, aiding researchers in understanding the role of peptides in neurological functions and disorders.
  • Protein Engineering: The compound is utilized in protein engineering to modify protein structures, enhancing their stability and functionality for various applications in biotechnology.

Citations