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Catalog Number:
32999
CAS Number:
186142-28-9
(Asn670,Leu671-Amyloid β/A4 Protein Precursor770 (667-676) trifluoroacetate salt
Synonym(s):
H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-OH trifluoroacetatesalt, (Asn670,Leu671)-APP770 (667-676)
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Product Information

The (Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-676) trifluoroacetate salt is a specialized peptide that plays a crucial role in Alzheimer's disease research. This compound is a fragment of the amyloid precursor protein (APP), which is significant in the formation of amyloid plaques, a hallmark of Alzheimer's pathology. Researchers utilize this peptide to study the mechanisms of amyloid plaque formation and to develop potential therapeutic strategies aimed at mitigating cognitive decline associated with Alzheimer's disease. Its trifluoroacetate salt form enhances solubility and stability, making it an ideal candidate for in vitro studies and drug development applications.

In addition to its relevance in neurodegenerative disease research, this peptide can be instrumental in the development of diagnostic tools and therapeutic agents targeting amyloid-related pathways. Its unique structure allows for specific interactions with amyloid-binding proteins, providing insights into protein aggregation processes. By employing this compound, researchers can explore innovative approaches to combat Alzheimer's disease, making it a valuable asset in both academic and pharmaceutical settings.

Synonyms
H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-OH trifluoroacetatesalt, (Asn670,Leu671)-APP770 (667-676)
CAS Number
186142-28-9
Molecular Formula
C50H78N14O19·C2HF3O2
Molecular Weight
1293.27
MDL Number
MFCD03787947
PubChem ID
85058590
Conditions
Store at ≤ -10 °C
General Information
Synonyms
H-Ser-Glu-Val-Asn-Leu-Asp-Ala-Glu-Phe-Arg-OH trifluoroacetatesalt, (Asn670,Leu671)-APP770 (667-676)
CAS Number
186142-28-9
Molecular Formula
C50H78N14O19·C2HF3O2
Molecular Weight
1293.27
MDL Number
MFCD03787947
PubChem ID
85058590
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(Asn670,Leu671)-Amyloid b/A4 Protein Precursor770 (667-676) trifluoroacetate salt is widely utilized in research focused on

  • Neuroscience Research: This compound plays a crucial role in studying Alzheimer's disease by mimicking amyloid-beta peptides, helping researchers understand the mechanisms of plaque formation in the brain.
  • Drug Development: It serves as a valuable tool in the development of therapeutic agents targeting amyloid-beta aggregation, providing insights that could lead to effective treatments for neurodegenerative disorders.
  • Biomarker Studies: The compound is used in identifying biomarkers for Alzheimer's disease, facilitating early diagnosis and monitoring disease progression.
  • Protein Interaction Studies: It aids in investigating protein-protein interactions, essential for understanding cellular processes and developing targeted therapies.
  • Peptide Synthesis: This trifluoroacetate salt is utilized in peptide synthesis protocols, enhancing the efficiency and yield of desired peptide products in pharmaceutical research.

Citations