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Catalog Number:
47394
CAS Number:
460751-66-0
Fmoc-5-bromo-L-triptófano
Purity:
≥ 99,5 % (HPLC quiral)
Synonym(s):
Fmoc-L-Trp(5-Br)-OH, Fmoc-Trp(5-Br)-OH
Documents
$70.00 /250 mg
Tamaño
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Información del producto

Fmoc-5-bromo-L-tryptophan is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethoxycarbonyl) group, which facilitates the selective coupling of amino acids during solid-phase peptide synthesis. Its unique 5-bromo substitution enhances its reactivity and allows for the introduction of bromine into peptide sequences, making it an invaluable tool for researchers aiming to create novel peptides with specific biological activities.

In the pharmaceutical industry, Fmoc-5-bromo-L-tryptophan is particularly relevant for the development of peptide-based therapeutics, including those targeting neurological disorders and cancer. Its ability to incorporate halogenated amino acids into peptides can lead to improved binding affinities and enhanced pharmacological properties. Researchers appreciate its stability and ease of use, which streamline the synthesis process while ensuring high purity and yield. This compound stands out for its potential to create complex peptide structures that can be tailored for specific applications in drug discovery and development.

Número CAS
460751-66-0
Fórmula molecular
C26H21BrN2O4
Peso molecular
505.4
Número MDL
MFCD28166519
Punto de fusión
190 - 200 °C (Literatura)
Condiciones
Conservar a 4 °C
Información general
Número CAS
460751-66-0
Fórmula molecular
C26H21BrN2O4
Peso molecular
505.4
Número MDL
MFCD28166519
Punto de fusión
190 - 200 °C (Literatura)
Condiciones
Conservar a 4 °C
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Fmoc-5-bromo-L-tryptophan is widely utilized in research focused on:

  • Peptide Synthesis: This compound is an essential building block in the synthesis of peptides, particularly in solid-phase peptide synthesis (SPPS), allowing researchers to create complex peptides with specific sequences.
  • Drug Development: Its unique structure makes it valuable in medicinal chemistry for developing new pharmaceuticals, especially those targeting neurological disorders, due to the tryptophan moiety's role in serotonin production.
  • Bioconjugation: The bromo group allows for selective reactions, making it useful in bioconjugation techniques to attach biomolecules to surfaces or other molecules, enhancing drug delivery systems.
  • Fluorescent Probes: The Fmoc group can be utilized in creating fluorescent probes for biological imaging, providing insights into cellular processes and molecular interactions.
  • Research in Neuroscience: Its application in studying neurotransmitter pathways helps researchers understand mood regulation and the biochemical basis of depression and anxiety.

Citas