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Catalog Number:
02483
CAS Number:
138797-71-4
Fmoc- O - terc -butil-D-treonina
Purity:
≥ 99% (ensayo)
Synonym(s):
Fmoc-D-Thr(tBu)-OH
Documents
$50.10 /1G
Tamaño
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Información del producto

Fmoc-O-tert-butyl-D-threonine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (9-fluorenylmethyloxycarbonyl) group, which allows for selective deprotection during the synthesis process, making it an essential building block for researchers in the field of medicinal chemistry. Its tert-butyl group enhances solubility and stability, facilitating smoother reactions and improving yields in peptide formation.

This compound is particularly valuable in the synthesis of peptides that require high purity and specificity, such as those used in therapeutic applications and vaccine development. Researchers appreciate its compatibility with various coupling reagents and its ability to streamline the synthesis of complex peptide structures. With its unique properties, Fmoc-O-tert-butyl-D-threonine stands out as a preferred choice for professionals seeking reliable and efficient solutions in peptide chemistry.

Número CAS
138797-71-4
Fórmula molecular
C23H27Nº 5
Peso molecular
397.5
Número MDL
MFCD00080292
Punto de fusión
128 - 142 °C (Literatura)
Rotación óptica
[a] D20
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
138797-71-4
Fórmula molecular
C23H27Nº 5
Peso molecular
397.5
Número MDL
MFCD00080292
Punto de fusión
128 - 142 °C (Literatura)
Rotación óptica
[a] D20
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Fmoc-O-tert-butyl-D-threonine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups. This is crucial for researchers developing new therapeutic peptides.
  • Drug Development: It is used in the design of peptide-based drugs, particularly in the pharmaceutical industry, where its stability and ease of removal make it a preferred choice for creating bioactive compounds.
  • Bioconjugation: The chemical is effective in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the functionality of diagnostic tools and therapeutics.
  • Protein Engineering: Researchers utilize it in the modification of proteins to study structure-function relationships, which is essential for developing new enzymes or antibodies with improved characteristics.
  • Research in Chemical Biology: It plays a role in chemical biology studies, where it aids in the exploration of cellular processes and interactions, helping scientists understand disease mechanisms and identify potential drug targets.

Citas