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Catalog Number:
02449
CAS Number:
86060-90-4
Éster pentafluorofenilo de Fmoc-L-prolina
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc-L-Pro-OPfp, (Éster pentafluorofenil del ácido S -Fmoc-pirrolidina-2-carboxílico
Documents
$29.34 /1G
Tamaño
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Información del producto

Fmoc-L-proline pentafluorophenyl ester is a versatile and highly valuable compound in the field of peptide synthesis and medicinal chemistry. This compound serves as a protective group for amino acids, particularly in the solid-phase peptide synthesis process, where it enhances the stability and solubility of the intermediates. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) group, allows for easy removal under mild conditions, making it an ideal choice for researchers looking to streamline their synthesis workflows.

Moreover, the incorporation of the pentafluorophenyl moiety not only increases the lipophilicity of the compound but also improves its reactivity, making it suitable for a variety of applications in drug development and bioconjugation. Researchers have successfully utilized Fmoc-L-proline pentafluorophenyl ester in the synthesis of bioactive peptides and complex natural products, showcasing its potential in developing therapeutics with enhanced efficacy. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of the amino acid structure positions it as a crucial tool for professionals in the pharmaceutical and biotechnology sectors.

Número CAS
86060-90-4
Fórmula molecular
C26H18Nº4F5
Peso molecular
503.4
Número MDL
MFCD00065672
Punto de fusión
122-130 ºC
Rotación óptica
[a] D 20 = -57 a -64º (c=1% en CHCl3)
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
86060-90-4
Fórmula molecular
C26H18Nº4F5
Peso molecular
503.4
Número MDL
MFCD00065672
Punto de fusión
122-130 ºC
Rotación óptica
[a] D 20 = -57 a -64º (c=1% en CHCl3)
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Fmoc-L-proline pentafluorophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing for the introduction of proline residues with high efficiency and specificity.
  • Drug Development: It is used in the design of pharmaceutical compounds, particularly in creating peptide-based drugs that target specific biological pathways, enhancing therapeutic efficacy.
  • Bioconjugation: The ester can be employed in bioconjugation techniques, linking biomolecules to surfaces or other molecules, which is crucial in developing biosensors and drug delivery systems.
  • Research in Protein Engineering: It aids researchers in modifying proteins to study structure-function relationships, providing insights into protein behavior and interactions.
  • Fluorinated Compound Applications: The presence of fluorine enhances the stability and bioavailability of compounds, making it valuable in various applications in medicinal chemistry.

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