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Catalog Number:
31939
CAS Number:
2044710-18-9
N α -Fmoc- N ε -4-metoxi-tritil-D-lisina
Purity:
≥ 99% (HPLC quiral, HPLC)
Synonym(s):
Fmoc-D-Lis(Mmt)-OH, Fmoc-D-Lys(4-metoxitritil)-OH
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Product Information

Na-Fmoc-Ne-4-methoxyyltrityl-D-lysine is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a protective Fmoc (fluorenylmethyloxycarbonyl) group, which is essential for the selective protection of amino groups during the synthesis of complex peptides. Its unique trityl and methoxy substituents enhance its stability and solubility, making it an ideal choice for researchers working on solid-phase peptide synthesis and other organic synthesis applications.

In the pharmaceutical industry, Na-Fmoc-Ne-4-methoxyyltrityl-D-lysine is particularly valuable for the development of peptide-based therapeutics, including those targeting specific receptors or enzymes. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of the amino acid structure allows for the creation of highly specific and effective drug candidates. Researchers appreciate its compatibility with various coupling reagents and its role in improving the yield and purity of synthesized peptides, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-D-Lis(Mmt)-OH, Fmoc-D-Lys(4-metoxitritil)-OH
CAS Number
2044710-18-9
Purity
≥ 99% (HPLC quiral, HPLC)
Molecular Formula
C41H40N2O5
Molecular Weight
640.8
MDL Number
MFCD00270631
PubChem ID
20643474
Melting Point
126 - 130 °C (Literatura)
Appearance
Polvo de color beige o blanquecino
Optical Rotation
[a] D 20 = 9 ± 1 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-D-Lis(Mmt)-OH, Fmoc-D-Lys(4-metoxitritil)-OH
CAS Number
2044710-18-9
Purity
≥ 99% (HPLC quiral, HPLC)
Molecular Formula
C41H40N2O5
Molecular Weight
640.8
MDL Number
MFCD00270631
PubChem ID
20643474
Melting Point
126 - 130 °C (Literatura)
Appearance
Polvo de color beige o blanquecino
Optical Rotation
[a] D 20 = 9 ± 1 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Na-Fmoc-Ne-4-methoxyyltrityl-D-lysine is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids. Its stability under various conditions makes it ideal for complex peptide sequences.
  • Drug Development: In pharmaceutical research, it is used to create peptide-based drugs. The ability to modify the lysine residue enhances the therapeutic potential of peptides, making them more effective in targeting specific biological pathways.
  • Bioconjugation: The compound is valuable in bioconjugation processes, where it helps attach peptides to other biomolecules, such as antibodies or enzymes. This application is crucial in developing targeted therapies and diagnostics.
  • Research in Cancer Therapy: Researchers utilize this chemical in the design of peptide conjugates that can selectively deliver drugs to cancer cells, improving treatment efficacy while minimizing side effects.
  • Protein Engineering: It plays a role in modifying proteins to enhance their stability and functionality. This is particularly useful in creating proteins with improved characteristics for industrial applications or therapeutic use.

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