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Catalog Number:
26718
CAS Number:
203866-21-1
Fmoc-4,4-difluoro-L-Prolina
Purity:
≥ 97 % (HPLC)
Synonym(s):
(Ácido 2 S -Fmoc-4,4-difluoro-pirrolidin-2-carboxílico
Documents
$134.70 /25 mg
Tamaño
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Product Information

Fmoc-4,4-difluoro-L-Proline is a highly valuable amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound features a unique difluorinated proline structure, which enhances the stability and bioactivity of peptides, making it an essential building block for researchers developing novel therapeutics. Its Fmoc (9-fluorenylmethyloxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing excellent protection during synthesis. The difluorination imparts distinctive properties that can improve the pharmacokinetic profiles of peptides, making them more effective in various applications, including drug development and molecular biology studies.

Researchers and industry professionals can leverage Fmoc-4,4-difluoro-L-Proline in the design of peptide-based drugs, particularly in targeting specific biological pathways or enhancing binding affinities. Its unique characteristics make it a preferred choice for those looking to innovate in peptide chemistry. With its ability to facilitate the creation of more stable and effective peptide constructs, this compound stands out as a crucial tool for advancing research in medicinal chemistry and biochemistry.

Synonyms
(Ácido 2 S -Fmoc-4,4-difluoro-pirrolidin-2-carboxílico
CAS Number
203866-21-1
Purity
≥ 97 % (HPLC)
Molecular Formula
C20H17F2NO4
Molecular Weight
373.35
MDL Number
MFCD01860709
PubChem ID
18623711
Appearance
Sólido de color blanco a blanquecino
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
(Ácido 2 S -Fmoc-4,4-difluoro-pirrolidin-2-carboxílico
CAS Number
203866-21-1
Purity
≥ 97 % (HPLC)
Molecular Formula
C20H17F2NO4
Molecular Weight
373.35
MDL Number
MFCD01860709
PubChem ID
18623711
Appearance
Sólido de color blanco a blanquecino
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-4,4-difluoro-L-Proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the incorporation of unique fluorinated amino acids that can enhance the stability and bioactivity of the resulting peptides.
  • Drug Development: Its unique properties make it valuable in pharmaceutical research, where it can be used to design and optimize drug candidates with improved pharmacokinetic profiles, potentially leading to more effective therapies.
  • Bioconjugation: The fluorinated structure aids in bioconjugation processes, enabling the attachment of biomolecules to drugs or imaging agents, which is crucial in targeted therapy and diagnostics.
  • Material Science: In polymer chemistry, it can be employed to create fluorinated polymers with enhanced chemical resistance and thermal stability, making it suitable for high-performance materials in various industrial applications.
  • Research in Fluorine Chemistry: This compound is instrumental in studies exploring the effects of fluorination on biological activity, providing insights that can lead to the development of novel compounds with tailored functions.

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