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Catalog Number:
37680
CAS Number:
69308-37-8
R -Baclofeno
Purity:
≥ 95% (ensayo por titulación, HPLC)
Synonym(s):
(Ácido R -4-amino-3-(4-clorofenil)butírico
Hazmat
Documents
$104.26 /25 mg
Tamaño
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Product Information

(R)-Baclofen is a potent muscle relaxant and antispastic agent that is widely utilized in the treatment of spasticity resulting from conditions such as multiple sclerosis and spinal cord injuries. This compound acts primarily as a GABA-B receptor agonist, which helps to inhibit excessive neuronal activity, thereby providing relief from muscle stiffness and spasms. Its unique structure, featuring a chlorophenyl group, enhances its efficacy and selectivity, making it a preferred choice in both clinical and research settings.

In addition to its therapeutic applications, (R)-Baclofen has garnered attention in the field of neuroscience for its potential in studying synaptic transmission and plasticity. Researchers have explored its role in modulating neurotransmitter release, which could lead to advancements in understanding various neurological disorders. The compound's favorable safety profile and effectiveness make it an invaluable tool for both healthcare professionals and researchers seeking to improve patient outcomes or explore new therapeutic avenues.

Synonyms
(Ácido R -4-amino-3-(4-clorofenil)butírico
CAS Number
69308-37-8
Purity
≥ 95% (ensayo por titulación, HPLC)
Molecular Formula
C10H12ClNO2
Molecular Weight
213.66
MDL Number
MFCD01321057
PubChem ID
2284
Melting Point
176 °C (descenso)
Appearance
Polvo blanco a casi blanco a cristalino.
Optical Rotation
[a]20D = 7 - 8 ° (C=1,6 mol/L en HCl)
Conditions
Conservar entre 2 y 8 °C.
General Information
Synonyms
(Ácido R -4-amino-3-(4-clorofenil)butírico
CAS Number
69308-37-8
Purity
≥ 95% (ensayo por titulación, HPLC)
Molecular Formula
C10H12ClNO2
Molecular Weight
213.66
MDL Number
MFCD01321057
PubChem ID
2284
Melting Point
176 °C (descenso)
Appearance
Polvo blanco a casi blanco a cristalino.
Optical Rotation
[a]20D = 7 - 8 ° (C=1,6 mol/L en HCl)
Conditions
Conservar entre 2 y 8 °C.
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-Baclofen is widely utilized in research focused on

  • Treatment of Muscle Spasticity: Commonly prescribed for conditions like multiple sclerosis and spinal cord injuries, it helps reduce muscle stiffness, improving mobility and quality of life for patients.
  • Neuropathic Pain Management: This compound is effective in alleviating pain associated with nerve damage, providing an alternative for patients who may not respond well to traditional pain medications.
  • Alcohol Dependence Therapy: Emerging studies suggest (R)-Baclofen can aid in reducing cravings and withdrawal symptoms in individuals with alcohol use disorder, offering a new avenue for treatment.
  • Research in Neuropharmacology: It serves as a valuable tool for scientists studying the central nervous system, helping to understand mechanisms of action in neurotransmission and potential therapeutic targets.
  • Veterinary Medicine: Used in animals, particularly for treating muscle spasms and pain, it demonstrates versatility beyond human applications, benefiting veterinary practices.

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