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Catalog Number:
29714
CAS Number:
1864002-98-1
Ácido (2 S , 4 R )-Fmoc-4-( N '-Pbf-guanidino)-pirrolidina-2-carboxílico
Purity:
≥ 97 % (HPLC)
Documents
$273.61 /25 mg
Tamaño
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Product Information

The compound (2S, 4R)-Fmoc-4-(N'-Pbf-guanidino)-pyrrolidine-2-carboxylic acid is a versatile building block widely utilized in peptide synthesis and drug development. Its unique structure, featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group, allows for selective deprotection, making it an essential tool for chemists in the field of medicinal chemistry. This compound is particularly valuable in the synthesis of guanidino-containing peptides, which have shown significant potential in therapeutic applications, including anti-cancer and anti-viral agents.

Researchers appreciate its stability and ease of handling, which facilitate streamlined synthesis processes. The incorporation of the Pbf (2,2,4,6,7-pentamethyl-3H-1-benzofuran-5-yl) group enhances the compound's solubility and reactivity, further broadening its applicability in various chemical reactions. As a result, this compound stands out for its ability to support complex peptide architectures, making it a preferred choice for professionals aiming to innovate in drug design and development.

CAS Number
1864002-98-1
Purity
≥ 97 % (HPLC)
Molecular Formula
C34H38N4O7S
Molecular Weight
646.76
MDL Number
MFCD18782849
PubChem ID
137796191
Appearance
Polvo blanco
Optical Rotation
[a] 20 D = + 9 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
CAS Number
1864002-98-1
Purity
≥ 97 % (HPLC)
Molecular Formula
C34H38N4O7S
Molecular Weight
646.76
MDL Number
MFCD18782849
PubChem ID
137796191
Appearance
Polvo blanco
Optical Rotation
[a] 20 D = + 9 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S, 4R)-Fmoc-4-(N'-Pbf-guanidino)-pyrrolidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of complex peptide chains.
  • Drug Development: It plays a significant role in the development of novel therapeutics, especially in the design of guanidino-containing compounds that can target specific biological pathways.
  • Bioconjugation: The chemical is used in bioconjugation processes, allowing researchers to attach biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Biochemistry: It is employed in biochemical research to study protein interactions and enzyme activities, providing insights into cellular functions and disease mechanisms.
  • Modification of Amino Acids: This compound is useful for modifying amino acids to enhance their properties, leading to improved stability and functionality in various applications, including enzyme engineering.

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