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Catalog Number:
29701
CAS Number:
1310680-34-2
Ácido R -Fmoc-3-amino-4,4,4-trifluoro-butírico
Purity:
≥ 99 % (HPLC)
Documents
$168.35 /25 mg
Tamaño
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Product Information

(R)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique trifluoromethyl group, enhancing its reactivity and stability, making it an excellent choice for researchers focused on developing novel therapeutics. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptides with high purity and yield. Its application extends to the production of fluorinated amino acids, which are increasingly important in medicinal chemistry for improving the pharmacokinetic properties of drug candidates.

In addition to its role in peptide synthesis, (R)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid is also valuable in the study of protein interactions and structure-function relationships. The trifluoromethyl group can impart unique electronic properties, making it a useful tool for probing biological systems. Researchers in pharmaceutical and biochemistry fields will find this compound indispensable for advancing their work in drug discovery and development, particularly in the creation of fluorinated compounds that exhibit enhanced biological activity.

CAS Number
1310680-34-2
Purity
≥ 99 % (HPLC)
Molecular Formula
C 19 H 16 F 3 NO 4
Molecular Weight
379.34
MDL Number
MFCD18782841
PubChem ID
22661402
Appearance
Polvo blanco
Optical Rotation
[α] D = +12 ± 2º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
CAS Number
1310680-34-2
Purity
≥ 99 % (HPLC)
Molecular Formula
C 19 H 16 F 3 NO 4
Molecular Weight
379.34
MDL Number
MFCD18782841
PubChem ID
22661402
Appearance
Polvo blanco
Optical Rotation
[α] D = +12 ± 2º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-Fmoc-3-amino-4,4,4-trifluoro-butyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing for the selective modification of amino acids without interfering with other functional groups.
  • Drug Development: Its unique trifluoromethyl group enhances the bioactivity and stability of pharmaceutical compounds, making it valuable in the design of new drugs.
  • Bioconjugation: The compound can be used to create bioconjugates, linking biomolecules like proteins and antibodies to therapeutic agents, which is essential in targeted drug delivery systems.
  • Research in Fluorinated Compounds: It provides insights into the behavior of fluorinated amino acids, contributing to studies in medicinal chemistry and materials science.
  • Analytical Chemistry: This chemical can be employed in chromatography and mass spectrometry for the analysis of complex mixtures, improving the accuracy of analytical results.

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