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Catalog Number:
29698
CAS Number:
181128-48-3
Ácido ( S )-Fmoc-2-amino-4,4,4-trifluorobutírico
Purity:
≥ 98 % (HPLC)
Documents
$110.00 /25 mg
Tamaño
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Product Information

(S)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid is a versatile building block widely utilized in peptide synthesis and drug development. This compound features a unique trifluoromethyl group that enhances its biological activity and stability, making it an essential component in the design of fluorinated peptides. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptide structures with high purity and yield. Researchers in pharmaceutical and biochemistry fields appreciate its role in creating peptides with improved pharmacokinetic properties, which can lead to more effective therapeutic agents.

In addition to its applications in peptide synthesis, (S)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid is also valuable in the development of novel materials and as a reagent in organic synthesis. Its unique properties allow for enhanced solubility and stability in various solvents, making it suitable for diverse applications in research and industry. By incorporating this compound into your projects, you can leverage its advantages for innovative solutions in drug discovery and development.

CAS Number
181128-48-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C 19 H 16 F 3 NO 4
Molecular Weight
379.34
MDL Number
MFCD08532485
PubChem ID
46737291
Melting Point
150 - 155 °C (Literatura)
Appearance
Polvo/sólido de color blanco a blanquecino
Optical Rotation
[a] D 20 = -33 ± 2 ° (C=1 en DMF) D 20 = -21 ± 2 ° (C=1 en CH3CN)
Conditions
Conservar entre 0 y 8 °C.
General Information
CAS Number
181128-48-3
Purity
≥ 98 % (HPLC)
Molecular Formula
C 19 H 16 F 3 NO 4
Molecular Weight
379.34
MDL Number
MFCD08532485
PubChem ID
46737291
Melting Point
150 - 155 °C (Literatura)
Appearance
Polvo/sólido de color blanco a blanquecino
Optical Rotation
[a] D 20 = -33 ± 2 ° (C=1 en DMF) D 20 = -21 ± 2 ° (C=1 en CH3CN)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid is widely utilized in research focused on

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids without affecting the overall peptide structure.
  • Drug Development: Its unique trifluoromethyl group enhances the pharmacological properties of peptides, making it valuable in the design of more effective therapeutic agents.
  • Bioconjugation: The compound is used to create stable linkages between biomolecules, facilitating the development of targeted drug delivery systems and improving the efficacy of biopharmaceuticals.
  • Research in Fluorinated Compounds: It allows researchers to explore the effects of fluorination on biological activity, providing insights into the design of novel compounds with enhanced properties.
  • Analytical Chemistry: The chemical is utilized in various analytical techniques, including NMR and mass spectrometry, to study the structure and dynamics of complex biological molecules.

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