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Catalog Number:
29636
CAS Number:
1072845-47-6
( S )-Fmoc-2-amino-2-metil-ácido succínico-4- tert -butil éster
Purity:
≥ 98 % (HPLC)
Synonym(s):
Fmoc-α-Me-L-Asp(OtBu)-OH
Documents
$168.35 /25 mg
Tamaño
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Product Information

(S)-Fmoc-2-amino-2-methyl-succinic acid-4-tert-butyl ester is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure not only enhances stability but also facilitates the efficient coupling of amino acids, making it a preferred choice for researchers in the fields of biochemistry and medicinal chemistry.

The tert-butyl ester group contributes to its lipophilicity, allowing for improved solubility in organic solvents, which is advantageous in various synthetic applications. This compound is particularly beneficial in the synthesis of complex peptides and can be employed in the development of pharmaceuticals, including peptide-based therapeutics. Its ability to streamline the synthesis process while maintaining high purity levels makes it an invaluable tool for chemists and researchers aiming to innovate in drug design and development.

Synonyms
Fmoc-α-Me-L-Asp(OtBu)-OH
CAS Number
1072845-47-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C24H27Nº6
Molecular Weight
425.48
MDL Number
MFCD12031692
PubChem ID
74391329
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = -18 a -12 ° (C=0,5 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-α-Me-L-Asp(OtBu)-OH
CAS Number
1072845-47-6
Purity
≥ 98 % (HPLC)
Molecular Formula
C24H27Nº6
Molecular Weight
425.48
MDL Number
MFCD12031692
PubChem ID
74391329
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = -18 a -12 ° (C=0,5 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(S)-Fmoc-2-amino-2-methyl-succinic acid-4-tert-butyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, allowing for the creation of complex peptide structures with high purity.
  • Drug Development: It plays a significant role in the pharmaceutical industry for developing new drug candidates, especially in designing peptide-based therapeutics that target specific biological pathways.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the effectiveness of drug delivery systems.
  • Research in Protein Engineering: Researchers utilize this chemical to modify proteins, improving their stability and functionality, which is crucial for various applications in biotechnology.
  • Analytical Chemistry: It is employed in analytical methods for characterizing peptides and proteins, providing insights into their structure and behavior in different environments.

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