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Catalog Number:
29119
CAS Number:
470482-41-8
(2 S , 4 S )- N -Boc-4-trifluorometilprolina
Purity:
≥ 98 % (HPLC)
Synonym(s):
Ácido (2 S ,4 S )-Boc-4-trifluorometil-pirrolidin-2-carboxílico
Documents
$120.88 /25 mg
Tamaño
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Product Information

(2S, 4S)-N-Boc-4-trifluoromethylproline is a valuable amino acid derivative that plays a significant role in peptide synthesis and drug development. This compound is particularly notable for its trifluoromethyl group, which enhances the lipophilicity and metabolic stability of peptides, making it an attractive choice for researchers in medicinal chemistry. Its N-Boc protection allows for selective deprotection under mild conditions, facilitating the synthesis of complex molecules. This compound is widely utilized in the pharmaceutical industry for the development of novel therapeutics, especially in the design of inhibitors and biologically active compounds.

The unique properties of (2S, 4S)-N-Boc-4-trifluoromethylproline make it an essential building block in the synthesis of peptide-based drugs. Its ability to introduce trifluoromethyl groups into peptide chains can lead to improved pharmacokinetic profiles and enhanced biological activity. Researchers have successfully employed this compound in various applications, including the development of antiviral agents and cancer therapeutics, showcasing its potential to contribute significantly to advancements in drug discovery and development.

Synonyms
Ácido (2 S ,4 S )-Boc-4-trifluorometil-pirrolidin-2-carboxílico
CAS Number
470482-41-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C11H16F3NO4
Molecular Weight
283.24
MDL Number
MFCD08460520
PubChem ID
67085600
Melting Point
121-129 ?C
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = -67 ± 2º (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Ácido (2 S ,4 S )-Boc-4-trifluorometil-pirrolidin-2-carboxílico
CAS Number
470482-41-8
Purity
≥ 98 % (HPLC)
Molecular Formula
C11H16F3NO4
Molecular Weight
283.24
MDL Number
MFCD08460520
PubChem ID
67085600
Melting Point
121-129 ?C
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = -67 ± 2º (C=1 en MeOH)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S, 4S)-N-Boc-4-trifluoromethylproline is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key building block in the synthesis of novel pharmaceuticals, particularly in the development of peptide-based drugs that target specific biological pathways.
  • Protein Engineering: It is used in the design of modified peptides and proteins, enhancing their stability and bioactivity, which is crucial for therapeutic applications.
  • Research in Neuroscience: The compound is valuable in studying neurotransmitter systems, as it can be incorporated into molecules that interact with receptors, aiding in the understanding of neurological disorders.
  • Material Science: Its unique properties allow for the creation of advanced materials with specific chemical functionalities, which can be applied in coatings and polymers.
  • Agrochemical Formulations: The compound finds applications in the development of agrochemicals, where it can enhance the efficacy of crop protection agents, contributing to sustainable agriculture practices.

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