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Catalog Number:
21484
CAS Number:
591-28-6
4-tiouracilo
Purity:
≥ 99 % (HPLC)
Synonym(s):
2-Hidroxi-4-mercaptopirimidina
Documents
$36.65 /250 mg
Tamaño
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Product Information

4-Thiouracil is a sulfur-containing derivative of uracil, known for its unique properties and applications in various fields, particularly in pharmaceuticals and biochemistry. This compound serves as a crucial intermediate in the synthesis of various therapeutic agents, including antithyroid medications, which are used to manage hyperthyroidism by inhibiting the synthesis of thyroid hormones. Its ability to act as a competitive inhibitor of the enzyme thyroperoxidase makes it invaluable in the treatment of thyroid-related disorders.

In addition to its pharmaceutical applications, 4-Thiouracil is also utilized in research settings, particularly in studies related to nucleic acid metabolism and enzyme inhibition. Its role in understanding the mechanisms of action of nucleoside analogs and its potential in developing new antiviral agents highlight its significance in the field of medicinal chemistry. Researchers appreciate its relatively straightforward synthesis and the versatility it offers in modifying nucleobases for various applications.

Synonyms
2-Hidroxi-4-mercaptopirimidina
CAS Number
591-28-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C4H4N2SO
Molecular Weight
128.16
MDL Number
MFCD00090842
PubChem ID
2734394
Appearance
Polvo amarillo
Conditions
Tienda en RT
General Information
Synonyms
2-Hidroxi-4-mercaptopirimidina
CAS Number
591-28-6
Purity
≥ 99 % (HPLC)
Molecular Formula
C4H4N2SO
Molecular Weight
128.16
MDL Number
MFCD00090842
PubChem ID
2734394
Appearance
Polvo amarillo
Conditions
Tienda en RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Thiouracil is widely utilized in research focused on:

  • Thyroid Disorders: It is commonly used in the treatment of hyperthyroidism, helping to reduce the production of thyroid hormones, thus managing conditions like Graves' disease effectively.
  • Antiviral Research: This compound has shown potential in research aimed at developing antiviral therapies, particularly against viral infections, by inhibiting viral replication.
  • Biochemical Studies: In laboratories, it serves as a valuable tool for studying the metabolism of pyrimidines and the role of sulfur in biological systems, providing insights into cellular processes.
  • Pharmaceutical Development: It is utilized in the synthesis of various pharmaceutical compounds, enhancing drug formulations by improving their efficacy and stability.
  • Research on Cancer Treatments: 4-Thiouracil is being explored for its potential in cancer therapies, particularly in targeting specific cancer cell pathways, making it a subject of interest in oncology research.

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