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Catalog Number:
14494
CAS Number:
203866-19-7
Ácido (2 S ,4 S )-Fmoc-4-fluoro-pirrolidin-2-carboxílico
Purity:
≥ 99 % (HPLC)
Synonym(s):
Fmoc- cis -4-fluoro-Pro-OH
Documents
$65.00 /100 mg
Tamaño
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Product Information

(2S,4S)-Fmoc-4-fluoro-pyrrolidine-2-carboxylic acid is a versatile building block in peptide synthesis, particularly valued for its role in the development of fluorinated amino acids. This compound features a unique fluorine atom that enhances the biological activity of peptides, making it an essential tool for researchers in medicinal chemistry and drug development. Its Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for easy incorporation into peptide chains while providing stability during synthesis.

In practical applications, this compound is utilized in the design of peptide-based therapeutics, where the incorporation of fluorinated residues can improve pharmacokinetic properties and metabolic stability. Researchers have successfully employed (2S,4S)-Fmoc-4-fluoro-pyrrolidine-2-carboxylic acid in the synthesis of bioactive peptides, showcasing its potential in advancing drug discovery and development. Its ability to enhance peptide performance makes it a valuable asset in both academic and industrial laboratories focused on innovative therapeutic solutions.

Synonyms
Fmoc- cis -4-fluoro-Pro-OH
CAS Number
203866-19-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C 20 H 18 N º 4 F
Molecular Weight
355.36
MDL Number
MFCD07781261
PubChem ID
4712599
Appearance
Polvo/sólido blanco
Optical Rotation
[a] D 20 = -40 ± 5 º (C=1 en CHCl 3 ) (Lit.)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc- cis -4-fluoro-Pro-OH
CAS Number
203866-19-7
Purity
≥ 99 % (HPLC)
Molecular Formula
C 20 H 18 N º 4 F
Molecular Weight
355.36
MDL Number
MFCD07781261
PubChem ID
4712599
Appearance
Polvo/sólido blanco
Optical Rotation
[a] D 20 = -40 ± 5 º (C=1 en CHCl 3 ) (Lit.)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,4S)-Fmoc-4-fluoro-pyrrolidine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a valuable building block in the synthesis of peptides, particularly in solid-phase peptide synthesis, enhancing the efficiency and yield of the process.
  • Drug Development: Its unique structure allows for the design of novel pharmaceutical compounds, particularly in the development of drugs targeting neurological disorders, where fluorinated compounds can improve bioavailability.
  • Bioconjugation: The chemical is used in bioconjugation applications, facilitating the attachment of biomolecules to surfaces or other molecules, which is crucial in creating targeted drug delivery systems.
  • Research in Organic Chemistry: It plays a significant role in organic synthesis, allowing chemists to explore new reaction pathways and develop innovative synthetic methodologies.
  • Analytical Chemistry: This compound can be utilized in analytical techniques, such as chromatography, to improve the separation and identification of complex mixtures, enhancing the accuracy of analytical results.

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