Descubra el nuevo Chem-Impex: donde la innovación comienza con un vínculo.

Catalog Number:
42451
CAS Number:
143664-11-3
Elacridar
Purity:
≥ 98 % (HPLC)
Synonym(s):
N- [4-[2-(3,4-Dihidro-6,7-dimetoxi-2(1 H -isoquinolinil)etil]fenil]-9,10-dihidro-5-metoxi-9-oxo-4-acridinacarboxamida
Documents
$259.39 /25 mg
Tamaño
Request Bulk Quote
Información del producto

Elacridar is a potent and selective inhibitor of P-glycoprotein, making it an invaluable compound in pharmaceutical research and drug development. This compound is particularly significant in enhancing the bioavailability of various therapeutic agents by preventing their efflux from cells, which is a common challenge in drug formulation. Researchers have utilized Elacridar to improve the absorption and efficacy of anticancer drugs, thereby facilitating more effective treatment regimens. Its unique structure allows it to cross the blood-brain barrier, making it a promising candidate for studies aimed at treating central nervous system disorders.

Elacridar's ability to modulate drug transport mechanisms positions it as a critical tool in the development of combination therapies, especially in oncology. By co-administering Elacridar with other chemotherapeutic agents, researchers can potentially overcome multidrug resistance, leading to improved patient outcomes. Its applications extend beyond oncology, as it is also being explored in the context of enhancing the delivery of various drugs across biological membranes. This compound not only supports innovative research but also holds the potential to revolutionize therapeutic strategies in multiple fields.

Número CAS
143664-11-3
Fórmula molecular
C34H33N3O5
Peso molecular
563.65
Número MDL
MFCD00912604
Punto de fusión
210 °C
Condiciones
Conservar a ≤ -4 °C
Información general
Número CAS
143664-11-3
Fórmula molecular
C34H33N3O5
Peso molecular
563.65
Número MDL
MFCD00912604
Punto de fusión
210 °C
Condiciones
Conservar a ≤ -4 °C
Propiedades
¡Pronto habrá más información sobre la propiedad!
-
Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Elacridar is widely utilized in research focused on:

  • Pharmaceutical Development: It is used as a potent inhibitor of P-glycoprotein, enhancing the bioavailability of various drugs by preventing their efflux from cells, which is particularly beneficial in formulating medications for cancer therapy.
  • Drug Combination Studies: Researchers employ Elacridar to study its effects in combination with other chemotherapeutic agents, aiming to improve treatment outcomes for resistant cancer types.
  • Transport Studies: It serves as a valuable tool in pharmacokinetic studies to assess how drugs are absorbed and distributed in the body, helping scientists understand drug interactions and optimize dosing regimens.
  • Neuroscience Research: Elacridar is utilized in studies examining the blood-brain barrier, aiding in the development of central nervous system-targeted therapies by evaluating how well drugs penetrate this barrier.
  • Formulation Science: It is applied in the development of novel drug delivery systems, enhancing the efficacy of poorly soluble compounds by improving their solubility and stability through innovative formulation techniques.

Citas