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Catalog Number:
22133
CAS Number:
25316-40-9
Clorhidrato de doxorrubicina
Grade:
Cumple con las especificaciones USP
Purity:
98 - 102% (ensayo, en base anhidra)
Synonym(s):
Clorhidrato de hidroxidaunorrubicina, Clorhidrato de adriamicina
Documents
$35.00 /25 mg
Tamaño
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Product Information

Doxorubicin hydrochloride is a potent anthracycline antibiotic widely utilized in oncology for its effective anti-cancer properties. This compound is primarily used in the treatment of various cancers, including breast cancer, bladder cancer, and leukemia, owing to its ability to intercalate DNA and inhibit topoisomerase II, leading to apoptosis in rapidly dividing cells. Its unique structure allows for enhanced cellular uptake, making it a critical component in combination chemotherapy regimens.

In addition to its therapeutic applications, Doxorubicin hydrochloride is also being explored in research settings for its potential in targeted drug delivery systems and nanomedicine, where its cytotoxic effects can be harnessed in a more controlled manner. The compound's versatility and effectiveness make it a valuable asset in both clinical and research environments, providing significant benefits in cancer treatment protocols and innovative therapeutic strategies.

Synonyms
Clorhidrato de hidroxidaunorrubicina, Clorhidrato de adriamicina
CAS Number
25316-40-9
Purity
98 - 102% (ensayo, en base anhidra)
Grade
Cumple con las especificaciones USP
Molecular Formula
C27H29NO11 · HCl
Molecular Weight
579.98
MDL Number
MFCD00077757
PubChem ID
21584061
Appearance
Polvo cristalino de color rojo anaranjado o rojo
Optical Rotation
[a]D20 = 240 - 290°
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Clorhidrato de hidroxidaunorrubicina, Clorhidrato de adriamicina
CAS Number
25316-40-9
Purity
98 - 102% (ensayo, en base anhidra)
Grade
Cumple con las especificaciones USP
Molecular Formula
C27H29NO11 · HCl
Molecular Weight
579.98
MDL Number
MFCD00077757
PubChem ID
21584061
Appearance
Polvo cristalino de color rojo anaranjado o rojo
Optical Rotation
[a]D20 = 240 - 290°
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Doxorubicin hydrochloride is widely utilized in research focused on

  • Cancer Treatment: This compound is a cornerstone in chemotherapy regimens for various cancers, including breast, lung, and leukemia. Its ability to intercalate DNA helps inhibit cancer cell growth effectively.
  • Combination Therapies: It is often used in combination with other anticancer drugs to enhance therapeutic efficacy and reduce the likelihood of drug resistance, providing a more comprehensive treatment approach.
  • Research in Drug Development: Doxorubicin hydrochloride serves as a model compound in the development of new anticancer agents, allowing researchers to study mechanisms of action and improve drug formulations.
  • Targeted Drug Delivery Systems: Researchers are exploring its use in nanotechnology, where it can be encapsulated in nanoparticles for targeted delivery, minimizing side effects and maximizing drug concentration at tumor sites.
  • Cardiotoxicity Studies: Due to its known side effects, it is frequently used in studies aimed at understanding and mitigating cardiotoxicity, helping to develop safer treatment protocols for patients.

Citas