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Catalog Number:
21690
CAS Number:
16096-97-2
L-ditiotreitol
Purity:
≥ 95% (Assay by titration)
Synonym(s):
(-)-1,4-Ditio-L-treitol, (-)-Reactivo de Cleland, ( 2R , 3R -(-)-2,3-Dihidroxi-1,4-butanoditiol
Documents
$110.00 /250 mg
Tamaño
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Información del producto

L-Dithiothreitol is a powerful reducing agent widely utilized in biochemical and molecular biology applications. This compound is particularly valued for its ability to maintain proteins in a reduced state, preventing oxidation during various experimental procedures. Its unique structure allows it to effectively break disulfide bonds, making it an essential reagent in protein purification, enzyme assays, and the stabilization of sensitive biomolecules. Researchers often employ L-Dithiothreitol in the preparation of samples for electrophoresis, as it enhances the resolution of proteins by ensuring they remain in their reduced form.

In addition to its role in protein chemistry, L-Dithiothreitol has shown potential in therapeutic applications, including its use in the treatment of oxidative stress-related conditions. Its ability to scavenge free radicals and protect cellular components from oxidative damage makes it a valuable compound in both research and clinical settings. With its broad range of applications and effectiveness in maintaining protein integrity, L-Dithiothreitol is an indispensable tool for scientists and industry professionals alike.

Número CAS
16096-97-2
Fórmula molecular
C4H10O2S2
Peso molecular
154.25
Número MDL
MFCD00064305
Punto de fusión
48 - 53 ?C
Rotación óptica
[a]D20 = 22 - 28 ° (C=2.5 in MeOH)
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
16096-97-2
Fórmula molecular
C4H10O2S2
Peso molecular
154.25
Número MDL
MFCD00064305
Punto de fusión
48 - 53 ?C
Rotación óptica
[a]D20 = 22 - 28 ° (C=2.5 in MeOH)
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

L-Dithiothreitol is widely utilized in research focused on:

  • Protein Stabilization: It is commonly used to maintain the reduced state of proteins during purification processes, preventing oxidation and preserving their functional integrity.
  • Cell Culture: In cell biology, it helps to reduce disulfide bonds in proteins, promoting cell viability and enhancing the growth of sensitive cell lines.
  • Biochemical Assays: Researchers use it in various assays to ensure accurate measurements of enzyme activity by keeping proteins in their active forms.
  • Antioxidant Applications: Its reducing properties make it effective in protecting cells from oxidative stress, which is crucial in studies related to aging and disease.
  • Drug Formulation: In pharmaceutical development, it serves as a stabilizing agent for certain drugs, improving their shelf life and efficacy.

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