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Catalog Number:
32288
CAS Number:
60-81-1
Florizina
Purity:
≥ 98 % (HPLC)
Documents
$22.03 /5G
Tamaño
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Product Information

Phlorizin is a naturally occurring dihydrochalcone glycoside, primarily found in the bark of apple trees and other plants. This compound is recognized for its significant role in the study of glucose transport and metabolism, making it a valuable tool in diabetes research. Phlorizin acts as a competitive inhibitor of the sodium-glucose transporters (SGLTs), which are crucial for glucose reabsorption in the kidneys. This property has led to its application in the development of SGLT inhibitors, a class of drugs that hold promise for managing type 2 diabetes by promoting glucose excretion and lowering blood sugar levels.

In addition to its pharmaceutical relevance, Phlorizin is also utilized in various biochemical assays and research applications, particularly in studies related to plant physiology and metabolism. Its antioxidant properties further enhance its appeal in the food and cosmetic industries, where it is explored for potential health benefits. With its multifaceted applications and ongoing research, Phlorizin continues to be an essential compound for both academic and industrial professionals seeking innovative solutions in health and nutrition.

CAS Number
60-81-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C21H24O10
Molecular Weight
436.41
MDL Number
MFCD00006591
PubChem ID
4789
Appearance
Polvo fino de color amarillo
Conditions
Conservar entre 2 y 8 °C.
General Information
CAS Number
60-81-1
Purity
≥ 98 % (HPLC)
Molecular Formula
C21H24O10
Molecular Weight
436.41
MDL Number
MFCD00006591
PubChem ID
4789
Appearance
Polvo fino de color amarillo
Conditions
Conservar entre 2 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Phlorizin is widely utilized in research focused on:

  • Diabetes Research: It is used to study glucose transport mechanisms and the effects of glucose on insulin secretion, providing insights into potential diabetes treatments.
  • Pharmacology: Researchers explore its role in understanding the pharmacokinetics of various drugs, particularly in how they interact with glucose transporters.
  • Plant Physiology: Phlorizin serves as a tool to investigate the effects of sugars on plant growth and development, aiding in agricultural research.
  • Neuroscience: It is applied in studies examining the neuroprotective effects of glucose modulation, contributing to the understanding of neurodegenerative diseases.
  • Natural Product Chemistry: Its presence in certain plants is studied for potential health benefits, leading to the development of natural health products.

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