Hydroxyurea is widely utilized in research focused on:

• Cancer Treatment: It is commonly used in chemotherapy regimens for certain types of cancer, particularly chronic myeloid leukemia and ovarian cancer, helping to slow down the growth of cancer cells.
• Sickle Cell Disease Management: Hydroxyurea is effective in increasing fetal hemoglobin levels, which can reduce the frequency of painful sickle cell crises and improve overall patient quality of life.
• Research on Genetic Disorders: It is used in studies investigating the genetic basis of diseases, as it can induce mutations in model organisms, aiding in the understanding of gene function and disease mechanisms.
• HIV Treatment: Hydroxyurea has been explored as an adjunct therapy in HIV treatment, as it may enhance the effectiveness of antiretroviral drugs by affecting viral replication.
• Dermatology Applications: In topical formulations, it is used to treat skin conditions like psoriasis and actinic keratosis due to its ability to promote cell turnover and reduce hyperkeratosis.