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Catalog Number:
22069
CAS Number:
7689-03-4
( S )-(+)-Camptotecina
Purity:
≥ 99% (ensayo)
Documents
$30.00 /1G
Tamaño
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Información del producto

(S)-(+)-Camptothecin is a potent alkaloid derived from the bark of the Camptotheca acuminata tree, renowned for its significant role in cancer treatment. This compound is particularly valued in the pharmaceutical industry for its ability to inhibit DNA topoisomerase I, an enzyme crucial for DNA replication and transcription. By interfering with this process, (S)-(+)-Camptothecin effectively induces apoptosis in cancer cells, making it a critical component in the development of chemotherapeutic agents. Its derivatives, such as topotecan and irinotecan, are widely used in clinical settings to treat various cancers, including ovarian and colorectal cancers.

In addition to its therapeutic applications, (S)-(+)-Camptothecin is also a subject of extensive research in drug formulation and delivery systems, where its unique structure allows for the development of novel anticancer therapies. Researchers are exploring its potential in combination therapies to enhance efficacy and reduce resistance in cancer treatment. With its proven effectiveness and ongoing research into its applications, (S)-(+)-Camptothecin remains a vital compound in the fight against cancer, offering hope for improved treatment outcomes.

Número CAS
7689-03-4
Fórmula molecular
C20H16N2O4
Peso molecular
348.35
Número MDL
MFCD00081076
Condiciones
Conservar entre 0 y 8 °C.
Información general
Número CAS
7689-03-4
Fórmula molecular
C20H16N2O4
Peso molecular
348.35
Número MDL
MFCD00081076
Condiciones
Conservar entre 0 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

(S)-(+)-Camptothecin is widely utilized in research focused on

  • Cancer Treatment: This compound is primarily known for its potent anti-cancer properties, particularly in the treatment of various types of cancer such as colorectal and ovarian cancers. It works by inhibiting DNA topoisomerase I, which is crucial for DNA replication.
  • Pharmaceutical Development: Researchers are actively exploring its derivatives to enhance efficacy and reduce side effects. This process is vital for developing new chemotherapy drugs that can target cancer cells more effectively.
  • Drug Formulation: (S)-(+)-Camptothecin is used in formulating targeted drug delivery systems. These systems aim to improve the bioavailability of the drug, ensuring that more of it reaches the tumor site while minimizing exposure to healthy tissues.
  • Research on Mechanisms of Action: It serves as a key compound in studies investigating the mechanisms of cancer cell resistance. Understanding these mechanisms can lead to better treatment strategies and improved patient outcomes.
  • Combination Therapies: This compound is often studied in combination with other chemotherapeutic agents to assess synergistic effects, potentially leading to more effective treatment regimens that can overcome drug resistance.

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