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Catalog Number:
38493
CAS Number:
58-58-2
Dihidrocloruro de puromicina de Streptomyces alboniger en polvo
Grade:
Adecuado para el cultivo celular.
Purity:
≥ 98 % (HPLC)
Synonym(s):
Clorhidrato de 3'-[a-amino-p-metoxihidrocinamido]-3'-desoxi-N,N-dimetiladenosina
Documents
$78.12 /25 mg
Tamaño
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Información del producto

Puromycin dihydrochloride from *Streptomyces alboniger* powder is a potent antibiotic and a valuable tool in molecular biology and biochemistry. This compound is widely recognized for its ability to inhibit protein synthesis in both prokaryotic and eukaryotic cells, making it an essential reagent in various research applications. Researchers utilize puromycin to select for genetically modified cells, as it allows for the effective identification of successfully transfected cells by inducing cell death in non-transfected cells. Its unique mechanism of action, which mimics aminoacyl-tRNA, enables it to bind to the ribosome and terminate peptide chain elongation, providing a reliable method for studying gene expression and protein function.

In addition to its applications in cell culture, puromycin dihydrochloride is also employed in the development of therapeutic strategies against cancer and infectious diseases. Its ability to selectively target and eliminate specific cell populations makes it a valuable asset in the field of targeted therapy. With its proven efficacy and versatility, puromycin dihydrochloride continues to be an indispensable compound for researchers and industry professionals seeking to advance their work in molecular biology and therapeutic development.

Número CAS
58-58-2
Fórmula molecular
C22H29N7O5 · 2HCl
Peso molecular
544.43
Número MDL
MFCD00012691
Punto de fusión
168 - 170 °C
Condiciones
Conservar a ≤ -10 °C
Información general
Número CAS
58-58-2
Fórmula molecular
C22H29N7O5 · 2HCl
Peso molecular
544.43
Número MDL
MFCD00012691
Punto de fusión
168 - 170 °C
Condiciones
Conservar a ≤ -10 °C
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
-
Aplicaciones

Puromycin dihydrochloride from Streptomyces alboniger powder is widely utilized in research focused on:

  • Cell Culture Research: This compound is commonly used as a selective agent in cell culture to eliminate untransformed cells, allowing researchers to maintain only those cells that have been successfully modified or transfected.
  • Antibiotic Applications: It serves as an effective antibiotic in microbiological studies, particularly in the selection of genetically modified organisms, ensuring that only the desired strains survive in a mixed population.
  • Biotechnology and Genetic Engineering: Puromycin is essential in the production of recombinant proteins, as it helps in the selection of cells that express the desired genes, streamlining the process of protein synthesis.
  • Cancer Research: Researchers utilize this compound to study the effects of protein synthesis inhibition on cancer cells, providing insights into potential therapeutic strategies for targeting tumor growth.
  • Pharmaceutical Development: It plays a role in drug discovery and development by aiding in the identification of new drug candidates that can effectively inhibit protein synthesis in pathogenic organisms.

Citas