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Catalog Number:
38304
CAS Number:
153436-53-4
Tirfostina AG 1478
Purity:
≥ 98 % (HPLC)
Synonym(s):
N- (3-clorofenil)-6,7-dimetoxi-4-quinazolinamina
Documents
$647.47 /25 mg
Tamaño
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Información del producto

Tyrphostin AG 1478 is a potent and selective inhibitor of receptor tyrosine kinases, particularly relevant in cancer research and therapeutic applications. This compound is recognized for its ability to interfere with signaling pathways that promote tumor growth and metastasis, making it a valuable tool for researchers investigating targeted cancer therapies. Its unique structure, featuring a 3-chlorophenyl group and dimethoxyquinazolin moiety, enhances its binding affinity and specificity, providing a significant advantage over other inhibitors in the same class.

In practical applications, Tyrphostin AG 1478 has been utilized in various studies to elucidate the role of tyrosine kinases in cellular processes, including proliferation and differentiation. Its effectiveness in modulating these pathways opens avenues for developing novel treatment strategies for cancers that are resistant to conventional therapies. Researchers can leverage this compound to explore its potential in combination therapies, thereby enhancing the efficacy of existing treatments and improving patient outcomes.

Número CAS
153436-53-4
Fórmula molecular
C16H14ClN3O2
Peso molecular
315.76
Número MDL
MFCD00270914
Punto de fusión
246 - 248 °C (descenso)
Condiciones
Conservar entre 2 y 8 °C.
Información general
Número CAS
153436-53-4
Fórmula molecular
C16H14ClN3O2
Peso molecular
315.76
Número MDL
MFCD00270914
Punto de fusión
246 - 248 °C (descenso)
Condiciones
Conservar entre 2 y 8 °C.
Propiedades
¡Pronto habrá más información sobre la propiedad!
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Seguridad y normativas
Materiales peligrosos
-
Antibiótico
-
Regulado por la DEA
No
Advertencias
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Aplicaciones

Tyrphostin AG 1478 is widely utilized in research focused on:

  • Cancer Research: This compound acts as a selective inhibitor of certain receptor tyrosine kinases, making it valuable in studying tumor growth and signaling pathways in cancer cells.
  • Neuroscience: It is used to investigate the role of specific kinases in neuronal signaling, helping researchers understand neurodegenerative diseases and potential therapeutic targets.
  • Drug Development: Tyrphostin AG 1478 serves as a lead compound in the development of new drugs aimed at inhibiting cancer cell proliferation, providing a basis for creating more effective therapies.
  • Cell Biology: The compound is employed in cell culture studies to elucidate the mechanisms of cell signaling and regulation, aiding in the understanding of cellular responses to external stimuli.
  • Biochemical Assays: It is frequently used in various assays to measure kinase activity, offering researchers a tool for screening potential inhibitors in drug discovery processes.

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