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Catalog Number:
38173
CAS Number:
58-14-0
Pirimetamina
Purity:
≥ 98% (ensayo por titulación, HPLC)
Synonym(s):
5-(4-clorofenil)-6-etil-2,4-pirimidindiamina
Hazmat
Documents
$52.68 /1G
Tamaño
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Product Information

Pyrimethamine is a potent antiprotozoal agent primarily used in the treatment of malaria and toxoplasmosis. This compound functions by inhibiting the dihydrofolate reductase enzyme, which is crucial for the synthesis of nucleic acids in parasites. Its effectiveness in combination therapies makes it a valuable asset in combating drug-resistant strains of malaria. Researchers and healthcare professionals appreciate Pyrimethamine not only for its therapeutic applications but also for its role in various studies related to folate metabolism and its potential effects on human health.

In addition to its medicinal uses, Pyrimethamine has found applications in agricultural settings as a pesticide, showcasing its versatility. Its unique structure allows for targeted action against specific pathogens, making it a preferred choice in both clinical and research environments. With ongoing studies exploring its potential in other therapeutic areas, Pyrimethamine remains a compound of significant interest for professionals seeking effective solutions in parasitic infections and beyond.

Synonyms
5-(4-clorofenil)-6-etil-2,4-pirimidindiamina
CAS Number
58-14-0
Purity
≥ 98% (ensayo por titulación, HPLC)
Molecular Formula
C12H13ClN4
Molecular Weight
248.71
MDL Number
MFCD00057350
PubChem ID
4993
Melting Point
239 - 243 °C
Appearance
Polvo blanco a casi blanco a cristal.
Conditions
Conservar entre 2 y 8 °C.
General Information
Synonyms
5-(4-clorofenil)-6-etil-2,4-pirimidindiamina
CAS Number
58-14-0
Purity
≥ 98% (ensayo por titulación, HPLC)
Molecular Formula
C12H13ClN4
Molecular Weight
248.71
MDL Number
MFCD00057350
PubChem ID
4993
Melting Point
239 - 243 °C
Appearance
Polvo blanco a casi blanco a cristal.
Conditions
Conservar entre 2 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pyrimethamine is widely utilized in research focused on:

  • Antimalarial Treatment: It is primarily used in the treatment and prevention of malaria, especially in combination with other medications like sulfadoxine. This dual therapy enhances efficacy and reduces resistance.
  • Antiparasitic Applications: Beyond malaria, it is effective against other parasitic infections such as toxoplasmosis, making it valuable in both human and veterinary medicine.
  • Research in Drug Development: Pyrimethamine serves as a model compound in pharmaceutical research, helping scientists develop new antimalarial drugs and study drug resistance mechanisms.
  • Veterinary Medicine: It is used in treating certain parasitic infections in animals, particularly in livestock and pets, ensuring animal health and productivity.
  • Synergistic Studies: Researchers explore its interactions with other drugs to improve treatment protocols, providing insights into combination therapies that can enhance patient outcomes.