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Catalog Number:
38097
CAS Number:
57149-07-2
Naftopidil
Purity:
≥ 98 % (HPLC)
Synonym(s):
1-[4-(2-Metoxifenil)piperazinil]-3-(1-naftiloxi)propan-2-ol
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Product Information

Naftopidil is a selective alpha-1 adrenergic antagonist primarily used in the treatment of benign prostatic hyperplasia (BPH). This compound is recognized for its ability to alleviate urinary symptoms associated with BPH by relaxing the smooth muscle in the prostate and bladder neck, thereby improving urine flow. Its unique structure, featuring a naphthalene moiety, enhances its binding affinity to alpha-1 receptors, making it an effective option for patients seeking relief from urinary obstruction.

In addition to its therapeutic applications, Naftopidil has been explored for its potential benefits in managing hypertension and other cardiovascular conditions due to its vasodilatory properties. Researchers and healthcare professionals appreciate Naftopidil for its favorable side effect profile compared to other alpha-blockers, making it a preferred choice in clinical settings. Its versatility and efficacy in addressing both urinary and cardiovascular issues highlight its significance in pharmaceutical formulations and patient care.

Synonyms
1-[4-(2-Metoxifenil)piperazinil]-3-(1-naftiloxi)propan-2-ol
CAS Number
57149-07-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C24H28N2O3
Molecular Weight
392.5
MDL Number
MFCD00242741
PubChem ID
4418
Melting Point
125 - 129 °C
Appearance
Polvo blanco a casi blanco a cristal.
Conditions
Conservar entre 2 y 8 °C.
General Information
Synonyms
1-[4-(2-Metoxifenil)piperazinil]-3-(1-naftiloxi)propan-2-ol
CAS Number
57149-07-2
Purity
≥ 98 % (HPLC)
Molecular Formula
C24H28N2O3
Molecular Weight
392.5
MDL Number
MFCD00242741
PubChem ID
4418
Melting Point
125 - 129 °C
Appearance
Polvo blanco a casi blanco a cristal.
Conditions
Conservar entre 2 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Naftopidil is widely utilized in research focused on:

  • Treatment of Benign Prostatic Hyperplasia (BPH): This compound is commonly prescribed to alleviate urinary symptoms associated with BPH, improving the quality of life for patients.
  • Cardiovascular Research: Naftopidil has been studied for its effects on blood pressure regulation, offering insights into potential treatments for hypertension.
  • Pharmacological Studies: Researchers use Naftopidil to explore its mechanisms of action as an alpha-1 adrenergic receptor antagonist, contributing to the understanding of receptor interactions.
  • Drug Development: Its unique properties make Naftopidil a candidate for developing new medications targeting similar conditions, providing a foundation for innovative therapies.
  • Clinical Trials: Naftopidil is often included in clinical studies to evaluate its efficacy and safety, helping to establish best practices in urology and cardiology.

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