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Catalog Number:
33080
CAS Number:
324017-23-4
Fmoc-Aph(Cbm)-OH
Purity:
≥ 99,5 % (HPLC quiral)
Synonym(s):
4-(Aminocarbonil)amino-N-Fmoc-L-Fenilalanina
Documents
$150.90 /100 mg
Tamaño
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Product Information

Fmoc-Aph(Cbm)-OH is a versatile amino acid derivative widely utilized in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino groups during the synthesis of peptides. Its unique structure, characterized by the incorporation of a carbamoylamino group, enhances its stability and reactivity, making it an ideal choice for researchers focused on developing complex peptide sequences.

In practical applications, Fmoc-Aph(Cbm)-OH is particularly valuable in the pharmaceutical industry for the synthesis of bioactive peptides, which can serve as potential therapeutics in various medical fields, including oncology and immunology. Its ability to facilitate the formation of peptide bonds while maintaining the integrity of sensitive functional groups makes it a preferred choice among chemists. Additionally, its compatibility with automated synthesizers streamlines the peptide synthesis process, improving efficiency and yield.

Synonyms
4-(Aminocarbonil)amino-N-Fmoc-L-Fenilalanina
CAS Number
324017-23-4
Purity
≥ 99,5 % (HPLC quiral)
Molecular Formula
C25H23N3O5
Molecular Weight
445.4
MDL Number
MFCD30475861
PubChem ID
85235280
Melting Point
198 - 203 °C (Literatura)
Appearance
Polvo blanquecino
Optical Rotation
[a] 20 D = -7 ± 3 ° (C = 1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
4-(Aminocarbonil)amino-N-Fmoc-L-Fenilalanina
CAS Number
324017-23-4
Purity
≥ 99,5 % (HPLC quiral)
Molecular Formula
C25H23N3O5
Molecular Weight
445.4
MDL Number
MFCD30475861
PubChem ID
85235280
Melting Point
198 - 203 °C (Literatura)
Appearance
Polvo blanquecino
Optical Rotation
[a] 20 D = -7 ± 3 ° (C = 1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-Aph(Cbm)-OH is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in solid-phase peptide synthesis, allowing researchers to create complex peptides with high purity and yield.
  • Drug Development: It is used in the design of peptide-based therapeutics, particularly in oncology and immunology, where precise peptide sequences can enhance drug efficacy.
  • Bioconjugation: The chemical's functional groups facilitate bioconjugation processes, enabling the attachment of peptides to various biomolecules for targeted drug delivery systems.
  • Research in Neuroscience: It plays a role in studying neuropeptides, which are crucial for understanding neurological functions and developing treatments for neurodegenerative diseases.
  • Biomaterials: Fmoc-Aph(Cbm)-OH is also explored in the development of biomaterials, particularly in tissue engineering, where its properties can aid in cell adhesion and growth.

Citas