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Catalog Number:
02448
CAS Number:
71989-31-6
Fmoc-L-prolina
Purity:
≥ 99,5 % (HPLC quiral)
Synonym(s):
Fmoc-L-Pro-OH, (Ácido S -Fmoc-pirrolidin-2-carboxílico
Documents
$18.53 /5G
Tamaño
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Product Information

El Fmoc-L-Proline se utiliza en la síntesis de péptidos para introducir prolina, un aminoácido conocido por inducir giros en las cadenas peptídicas y afectar la conformación general de péptidos y proteínas. El grupo protector Fmoc permite la adición secuencial de aminoácidos, y la prolina desempeña un papel fundamental en las relaciones estructura-actividad de los péptidos bioactivos, incluidos los péptidos de señalización, los inhibidores de enzimas y los péptidos antimicrobianos.

Synonyms
Fmoc-L-Pro-OH, (Ácido S -Fmoc-pirrolidin-2-carboxílico
CAS Number
71989-31-6
Purity
≥ 99,5 % (HPLC quiral)
Molecular Formula
C 20 H 19 N.º 4
Molecular Weight
337.4
MDL Number
MFCD00037122
PubChem ID
100106
Melting Point
100 - 118 ?C
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = -32 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
General Information
Synonyms
Fmoc-L-Pro-OH, (Ácido S -Fmoc-pirrolidin-2-carboxílico
CAS Number
71989-31-6
Purity
≥ 99,5 % (HPLC quiral)
Molecular Formula
C 20 H 19 N.º 4
Molecular Weight
337.4
MDL Number
MFCD00037122
PubChem ID
100106
Melting Point
100 - 118 ?C
Appearance
Polvo blanco
Optical Rotation
[a] D 20 = -32 ± 2 º (C=1 en DMF)
Conditions
Conservar entre 0 y 8 °C.
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-proline is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in solid-phase peptide synthesis, allowing for the selective formation of peptide bonds while preventing unwanted reactions. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, Fmoc-L-proline is used to create peptide-based drugs. Its ability to enhance the stability and bioavailability of therapeutic peptides is crucial in developing effective medications.
  • Bioconjugation: The compound is employed in bioconjugation processes to attach biomolecules to surfaces or other molecules. This application is vital in creating targeted drug delivery systems and diagnostic tools.
  • Protein Engineering: Researchers utilize Fmoc-L-proline in the design of modified proteins. Its unique structure allows for the incorporation of proline residues, which can influence protein folding and stability, leading to improved functionality.
  • Material Science: In the development of new materials, Fmoc-L-proline is used to create polymeric systems with specific properties. Its role in enhancing the mechanical and thermal properties of materials is beneficial in various industrial applications.

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